posted Wed, 12/26/2012 - 08:56
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Should I be taking Aromasin with my cycle.
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I need some advice. I understand why you take pct, but I don't understand what clomid does and so on. I am taking 600mg a week of test e, and 500mg a week of eqiupose. I am in my second week of my cycle. Should I be taking Aromasin eod?
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AnonOk, i've produced a breakdown for you in order to:
1) Uncerstand what Nolva is/does
2) Understand what an AI is
3) Understand the two types of AI
4) When to use an AI/PCT
5) Knowledge about PCT/SERMs
Nolvadex- increases in the serum levels of LH, FSH, and most importantly, testosterone. And also helps block estrogen. However, it helps your body increase your sperm count because of that. In fact the bad thing about Nolvadex unlike Clomid is that it doesn’t on its own increase sperm count or their motility. However, you still needed it because it does increase your LH and FSH which we need for healthy testis.
Aromatase Inhibitors come in 2 types. Type 1 and Type 2. First Type 1 AI's bind by a process called hydroxylation; this hydroxylation process produces an unbreakable covalent bond between the inhibitor and the enzyme protein. Now the enzyme is permanently blocked even after all of the inhibitor is removed and can only be resumed by new enzyme synthesis. Type 2 Inhibitors on the other hand function all the same in their ability to reduce the binding process of the enzyme and the receptor. Except once the drug is discontinued or the concentration of the drug is sparse enough it is possible for the enzyme to seperate itself from the Inhibitor and eventually will allow renewed competion between the Inhibitor and the Enzyme for the receptor site. Aromasin is a type 1 AI and once it does what it's purpose is we don't need to continue use. Letro and Adex are Type 2 Ai's and the success of those drugs are continigent on the Doses and protocol of which we use them. Once you stop them you expose yourself to an Estrogen rebound. Now having said all of that there are also many other reason to why Aromasin use is beneficial to a Bodybuilder. One is Arimidex/Anastrozole Decreases IGF-1 18% while Aromasin/Exemestane Increases IGF-1 28%. Another is Aromasin is also known to decrease estrogen between 90-95% while boosting Endogenous Testosterone by about 60%, and also help out your free to bound testosterone ratio by lowering levels of Sex Hormone Binding Globulin (SHBG), by about 20% (12)…SHBG is that nasty enzyme that binds to testosterone and renders it useless for building muscle.
SERM- Selective Estrogen Receptor Modulator- are a class of compounds that act on the estrogen receptor. A characteristic that distinguishes these substances from pure receptor agonists and antagonists is that their action is different in various tissues, thereby granting the possibility to selectively inhibit or stimulate estrogen-like action in various tissues. Clomid and Nolvadex are examples of these.
Mode of Action for SERM
Estrogenic compounds span a s
pectrum of activity ranging from:
1) Full agonists (agonistic in all tissues) such as the natural endogenous hormone estrogen
2) Mixed agonists/antagonistics (agonistic in some tissues while antagonist in others) such as tamoxifen (a SERM)
3) Pure antagonists (antagonistic in all tissues) such as fulvestrant (ICI-182780).
You want either adex/asin on cycle at the following doses:
Aromasin @ 12.mg EOD
Arimidex 0.25mg EOD if nipples get sore than 0.5mg EOD if still sore 0.5mg EOD.
Aromast when estro begins to Pop up...bout week 4. Bloat...itchy nips.....depressed...no libido.
Pct with aro since it raises igf
Aro 12.5 12.5 6.75 6.75
Clomid 100...100..50...50
Nolva 20...20...10..10
Aro runs right into pct. Im wondering stats...priors?
Post your stats/cycle/experience. You sound like you're on first cycle and need more help
You're running half the nolva most guys suggest. Is that because you've included the aro? I don't pct so I'm just curious.
Yessir.. Nolva is your nipple blocker. So estrogen is still floats in your bloodstream. Let the aro control all the loose estro.. Then nolva has easier time blocking and sending signals for recovery. Less nolva blues and raise in igf.
Makes sense to me. I haven't ran pct in a few years but I've seen a lot of guys going more the route that you layed out. Thanks for learning me bro.
The bloodtest showed faster recovery and less blah. So you just run aro or adex past cycle for blast/cruise?
Basically. I run adex with my prop when I'm blasting and aro with cyp or enanthate when I cruise. I like how much better aromasin does with bloat while on the long esters but it dries my joints out too much if I run it with prop. Probably just in my head but it does seem to work best for me.
Sounds very reasonable. Its a bonus when you know your body.
I am 33 years old 5'11" 192 10% bf. And I dip and dap here and ther real low dosages.
Ok...well your dip n dappin in big leagues. Eq/test is my favorite. So post your cycle becausr its not sounding like you know what your doing.
Clomid and nolva help jump start your natural system after its been repressed by exogenous compounds. You should absolutely run aromasin at least eod. Is this your first cycle? Sounds like it.
Cool thank you. I have been taking aromasin since first shot just double checking. I didn't know if you had to wait.
You asked the right questions. Just keep reading and you'll be fine brother. Definitely headed in the right direction.
I started my aromasin on week one. I kickstarted with prop tho, and I have a small gyno lump from previous cycle (long story) so I'm not taking chances, I'm starting week 4 now and I'm talking the aromasin like 3 days on 2 days off, everyone's different u have to find your sweet spot, I agree with OM , start @ 6.25 and work up to 12.5 and its best to use aromasin daily
Yeah you should start an AI week 1 with prop. I run adex with prop and aromasin with cyp or enanthate. Aromasin tends to dry my joints out more but it's far more effective with the bloat caused by enanthate.
You should be taking aromasin ed at 6.25 or 12.5mg on week 3 or 4.. Is this your first cycle? You need clomid and nolva on hand for pct and don't wait till the week before to get it.
Why aromasin not from week 1 at 6.25 ed?
Because it would be a waste and could actually cause e2 levels to dip a little low while you're waiting on the long estered enanthate to kick in. It has a half life of around 14 days.
The esters being used don't kick in until week 3-5 normally.. varies for diff ppl.. Usually you KNOW when the nips get itchy or you feel a lil bloated
But to play it safe I start by week four at the latest with test E
Alright if you have dbol as kicker you can throw in aromasin if you feel bloatet after week 2..
If I run dbol as a kicker I'm running aromasin at 12.5mg ed starting day 1. Dbol is strong and heavily aromatizes.
Yes yes!