Dim
Anyone actually get blood testing done to see if dim actually plays a role in lowering estrogen? I don’t doubt it does but let’s say someone has elevated estrogen once TRT, at which point is dim a viable option vs taking an AI? Like are we talking a few points your e2 might drop when on dim consistently? Or could you drop 10 points or more? Obviously everyone’s different but I assume a rough estimate would be pretty accurate person to person. I doubt someone can go from 70 down to 50 so what’s your opinion? Are we talking a few points dropped or more than 10? I’m guessing it could get you in range if you’re 2-5 over. I like to try “natural” things (i know it’s not actually natural but you know what I mean) before I go for pharmaceuticals.
Article I found in dim effecting androgens in the body
https://atpscience.com.au/blogs/hormones/dim-diindolylmethane-the-most-p...
Snippet from the website
DIM - Diindolylmethane is an androgen antagonist!
DIM blocks the effects of testosterone. Higher doses (greater than 100mg) of isolated pure DIM can saturate tissues and block androgen (e.g. testosterone and dihydrotestosterone) receptors and inhibit the protein synthesis induced by the anabolic effects of androgens. This is one of the ways DIM can help in cases of prostate cancer; the other way is by inhibiting mTOR pathways that lead to cell growth and division but we will discuss mTOR in greater detail later when we discuss muscle hypertrophy.
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I'd rather have slower gains and a protected prostate. One day you wake up and go to drain the lizard and it just trickles out.... Ah the joys of getting old with many years of juice abuse. It's wonderful
I found this article online that says it could actually inhibit androgens. I’ll clip it in up top in my original post. It almost seems like it’s saying that while it’s not really an AI it actually takes e2 and converts it to a different estrogen that’s less aggressive and in turn it lowers e2 levels artificially. After doing alittle more digging it almost seems like taking 300mg a day might actually take away from your gains on TRT or a blast. Now like you said there’s very little info or studies so it could be completely wrong. I just thought it was interesting read.
Personally i always use strictly adex or aromSin that is pharma. The ancilliracies are crucial of you start having sides. High e2 also leads to high prolactin. Definitely gotta watch with running some of the big ones. Body fat plays a big roll in e2 conversion. So does the ester of test your running.
If you’re 55-60 and want to get closer to 40-45 DiM is a viable solution. If you’re at 80 DIM is more than likely not going to get you back in normal range and you’re going to need a rx AI. Not sure how does dependent it is. There isn’t much research on it. Most the recommendations I’ve seen are 300mg ed but I’ve heard of some people taking 600. I got on it when I started TRT per my doctors request but then decided to drop it because I wanted to see where my estrogen was without any AI on 150mg ew of test. And it was at 39. So no need for any AI. So I never did bloods while on it.
Yes. DIM and also Calcium D glucarate can bring you down from being a little over the reference range to within the reference range. It's not as strong as an AI. 100mg of DIM and 500mg of Calcium D glucarate taken AM and PM.
It works by accelerating the metabolism and clearance of E2. Not preventing the creation of it like an AI does. This is why its only good for mild E2 reduction.
I found this article online that says it could actually inhibit androgens. I’ll clip it in up top in my original post. It almost seems like it’s saying that while it’s not really an AI it actually takes e2 and converts it to a different estrogen that’s less aggressive and in turn it lowers e2 levels artificially. After doing alittle more digging it almost seems like taking 300mg a day might actually take away from your gains on TRT or a blast. Now like you said there’s very little info or studies so it could be completely wrong. I just thought it was interesting read.
It’s very person dependent