I’m not claiming to be an expert (or that I even remotely came up with this myself or have any personal experience), but this was new news and information to myself as I was researching. I find stuff like this endless fascinating and think that the nitty gritty of this stuff is really interesting. I did a quick search through the forums and didn’t find anything that actually broke down the science behind what the difference is between Proviron and Masteron is, so I thought I’d share what info I’d come across (any mistakes I would love corrections on). I would also love to hear any anecdotal information from people who prefer one over the other (reading this it seems like Masteron is far superior, and from my research cheaper), or who love running both. So lets get to it.

Proviron (1-methyl-dihydrotestosterone) and Masteron (2-methyl-dihydrotestosterne) are pretty damn similar. Basically its DHT with a minor methylation modification to them. I think a large number of people believe them to be interchangeable, and that Proviron is just an oral form and Masteron injectable form. They both bring to the table similar things. Zero estrogen conversion and a slight anti-estrogenic activity (non-aromatizable steroids complete with aromatized steroids for binding to the aromatase enzyme), this in turn should lower estrogen levels, and change the androgenic to estrogenic ratios. This should help push out subcutaneous water, increase muscularity, increase libdo, sense of wellbeing, possibly aggression. I really don’t think any of this really new.

I think it’s pretty commonly known Proviron using 1-methlation results in it being allowed to be taken orally. But it also appears to be it’s downfall when compared to Masteron. I’ve always heard DHT is so much more powerful than test. So why is DHT not a good muscle builder? Apparently, just like DHT, proviron has a high affinity for an enzyme called 3-alpha hydroxysteroid dehydrogenase or 3HSD. 3SHD is present in high amounts in muscle tissue, and when DHT and Proviron come in contact to it on its way to the muscle receptor. The 3SHD removes the 3-keto group from the active steroid molecule. Producing a weak steroid “diols”, basically a cleaved steroid molecule, and not very anabolic. This makes proviron and DHT poor anabolics.

So where does this leave Masteron? By simply shifting the methylation from 1 to 2, it does two things. One it doesn’t allow Masteron to be taken orally, but two (and more importantly) it protects the steroid molecule from being converted by 3HSD. Therefore, Masteron is able to enter the muscle, and make it to the androgen receptors whole and allowing it to help build muscle during a gaining phase, or retaining it during a dieting down period.

While I understand that Masteron is not going to be the strongest anabolic out there, when choosing between the two, wouldn’t you want to use the one that is more anabolic? The science makes it pretty cut and dry, but I understand often at times there is far more to it than that. I’d be interested to her from people who prefer Proviron over Masteron, and their experiences.