ED vs EOD?
Which do you guys do? I am talking about people with experience using both protocols. I was going to do ed but after ready this it has changed my mind. This was taken from steroid.com...
Finally, Ill tell you how Id take Human Growth Hormone, personally. There was a study done on continuous Human Growth Hormone use vs. every other day injections (ED vs. EOD for the sake of brevity), with a equal total weekly dose. Although its counter intuitive, every other day injections produced better total growth in the kids in this (2 and 4 year long) study. Take a look at these graphs:
Growth velocity of children treated with alternate day Human Growth Hormone (the darker bars) or with a daily Human Growth Hormone regimen before, during, and 2 yr after stopping therapy. Values are the mean SD. *, P < 0.05; **, P < 0.01.(10)
Heres another:
Pretreatment and cumulative 4-yr growth velocity of children treated with alternate day Human Growth Hormone ( the darker bars) or with a daily Human Growth Hormone regimen. Values are the mean SD. *, P < 0.00 (10)
Shooting Human Growth Hormone every other day more accurately replicates the pulsile frequency of Human Growth Hormone, and thus gave better results for growth (height) deficient children, Human Growth Hormone pulsatility is necessary for proper function of the Human Growth Hormone receptor.(10) Dosing in the EOD nature reduces incidence of any sort of withdrawal problems associated with normal Human Growth Hormone use, including regression or retardation of growth after cessation of therapy.
Therefore, I feel very comfortable speculating that the use of Human Growth Hormone in this manner, which more closely simulates the natural secretion pattern of it, allows the Human Growth Hormone receptors and the rest of the body to more efficiently recover from it, and this will result in much more muscle growth over time (although height was examined in the previous study). My recommendations therefore are 2 shots per day of .028iu/kg of body weight, taken every other day, for a minimum of 3months, and preferably for 2-3x that long, and preferably with the other synergistic compounds we've just taken a look at.
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I think the issue with this study is it was in reference to medical doses. The increase in IGF-1 lasts 36-48 hrs so eod would peak and drop. ED would maintain more consistent IGF-1 Levels. The issue with BB doses doubled and done eod will increase the risk of side affects such as Joint Pain. I tried it for a week and didn't like it.
UFOGood to know thanks
AnonIf you're talking about gh, the ideal would be ED. Especially considering the short half life. After 3.5 hrs, levels begin to decline.
actually I think that levels of GH after a shot BEGIN to raise at about 3.5 hours and then stay raised for around 7 hours before declining...isn't it? Hence the whole idea to get your blood test 3.5 hours after inject as the GH is at its peak. But your IGF levels begin elevating instantly and stay elevated for 24-48 hours after ONE inject. Someone correct me if I am wrong.
http://www.biomedcentral.com/content/figures/1472-6904-7-10-1-l.jpg
UFOSeems like ed is the way to go.
AnonGood job
Thanks Marky Mark, that's one of the graphs from the saizen report I was talking about. I have to find that full study again there was a lot more info in it.
well, that puts it in black and white!!
The graphs I've seen in the Saizen report were a more consistent ramp up and down starting immediately after injection lasting over a 7 hr period peaking at 3.5hrs. I did a quick search but didn't find them. I thought I posted it before I'll have to look and repost it. It showed the difference between IM and SubQ using their new * click method for IGF-1 and Serum HGH over many patients at like 15 min intervals.
OK, OK...that's more what I meant, lol...that there is a 7 hour period peaking at 3.5 hours, meaning the whole idea of the blood test 3.5 hours from inject. I was in a hurry typing and hopped in the shower after the gym!!
That's why I like to inject a couple hours before I hit the gym(most of the time) because technically at about the end of my workouts is when the GH would be at its peak and IMO encourages more growth and recovery...I always inject first thing in the morning regardless, but sometimes I don't get to the gym in the AM hours, oh well. I just always seem to have better energy levels in the AM as well, that's my time to shine, has been for years!!
AnonHmmm... Now you got me second guessing... I wanna say I remember reading that 7 hrs is how long it is active. I could be wrong.