GHRP-6

Growth hormone releasing peptide-6 (GHRP-6) is in the category of drugs known as GH Secretagogues. This category of drugs includes GHRP-2, GHRP-6, Ipamorelin, and Hexarelin. Their primary function is to stimulate the pituitary gland to produce more Growth Hormone. GHRPs have a 2-fold mechanism of action, in that they cause an increase in GH through amplifying the natural growth hormone releasing hormone (GHRH) signal transduction pathway, as well as by suppressing the actions of somatostatin.

GHRP-6 is a 1st generation GHRP and is primarily used in the research community for two reasons, which are 1) GH release and 2) Appetite stimulation. If researching this peptide for GH release, the researcher should consider whether or not the accompanying appetite stimulation is a beneficial or negative characteristic in their current circumstances. In researchers who struggle with appetite issues and have trouble eating enough food to meet their daily caloric requirements, this peptide can prove to be a great addition to their program. For those on contest diets or who are trying to lean out, they may want to forego this peptide in exchange for a GHRP absent of this effect.

Common benefits of GH (GHRP-6) include:

Reductions in body fat
Increased lean mass.
Increased collagen production
Improved sleep
Increased cellular repair
An increase in IGF-1
Increases in bone density

Common side effects of GH (GHRP-6) include:

Water retention
Tightness and/or carpel tunnel-like symptoms in the wrist/hand.
Numbness and tingling in the extremities
A decrease in insulin sensitivity
Tiredness