primordial_soup's picture
primordial_soup
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unsure if 1000iu of HcG/wk is sufficient to prevent testicular shrinkage from trenbolone(i need to be on trenbolone for mood)

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My questions are

  1. is 1000iu HcG sufficient to prevent testicular atrophy(ball shrinkage) on tren?

  2. is 90mg of tren weekly enough to boost mood significantly?(I know 3mg of metribolone helps a lot)

  3. at 180mg test E + 1000iu HcG, would 2mg letrozole weekly just crash my e2 and is this bad? Should I lower the dose of letrozole?

  4. is it safe to take 180 test e, 90 tren weekly for months on end? What could go wrong with my health(im taking tadalafil for blood pressure and i remove/donate blood almost monthly)?

Recently in the past month, my mood seems to have taken a huge dip somehow culminating in actual suicidal plans(i have something like multiple sclerosis with chronic pain, fatigue and memory loss/brain fog), but yesterday I experimented by taking 3mg of M-tren/metribolone and I felt a huge boost in mood focus and less depressed.

The 3mg has worn off from yesterday and im starting to feel upset once again and have anxiety and feel bad.

im already taking actual antidepressants bupropion(Wellbutrin) and it helps me feel better, but it isnt even half as effective as taking Proviron/mesterolone or M-tren/metribolone. There were scientific studies in the 1980s proving that mesterolone has equal efficacy to antidepressants in treating depressed men.

https://pubmed.ncbi.nlm.nih.gov/3880735/ (pirate the full medical article using Sci-hub.se)

So I've decided the only thing I know that could help my condition is to start injecting trenbolone weekly since you can't take M-tren regularly because it is hepatoxic.

My plan for the stack is to inject .9ml/wk of Test 200/Mast100/Tren100 mixture which would mean im taking
-180mg testosterone
-90mg of trenbolone
-90 mast
-1000iu HcG
- ~2mg letrozole

Also, 1000iu HcG/wk and ~2mg of letrozole weekly are split into 3 doses as well.

smurfdude1234567's picture

Can promise tren is not the answer. Maybe a slight temporary band-aid, but continued use for mood WILL blow up in your face.

Always be in a stable headspace before using drugs.

press1's picture

How are you feeling today mate, are you okay?

What do you think about trying to come of this Wellbutrin and maybe trying something else? From what members are saying it seems that may be doing more harm than good in the long run and making you feel worse?

press1's picture

Buddy - after reading more about this drug I really think it would be worth your while trying something else, it seems the side effects you are experiencing such as suicidal thoughts and worsening depression are a main side effect of this medication, it isn't the best rated for its effectiveness either:

https://www.drugs.com/tips/wellbutrin-patient-tips

Have you tried some of the better rated ones such as Lexapro, Zoloft or Citalopram?

primordial_soup's picture

whats suspicious is that i get the sense that my natural testosterone production has just been tanking from metribolone use, and my hemoglobin is extremely low lately

yesterday my hemoglobin was only 13.8 usually its 15.5-17.3(i get phlebotomy once it aproaches 17)

but i dont think my hemoglobin has ever been so low ever before? maybe when i was like a little kid before puberty.

it might be that my depressed mood is just from getting my natural testosterone production shut down by the usage of metribolone.

i might need to just take some time for post cyle therapy and recovery of natural production, maybe just taking HcG in high doses alone

press1's picture

From taking Mtren your natural testosterone levels will already be non existent, its one of the strongest steroids you can buy bud. You will now have to make sure you keep taking your TRT dose of testosterone as your natural stores will be gone currently. If you don't take the TRT dose you will feel depressed.

Your Haemoglobin is reliant on your Iron, Folate and B12 intake - do you take vitamins/supplements daily or eat a lot of red meat to help here? Haemoglobin can also be down to your kidney health too buddy - if they are suffering from the mtren which its likely they may be if you have been doing this routine for a while then your haemoglobin production will be lower as your kidneys together with your bone marrow help produce red blood cells. The haemoglobin size may have become disturbed while you have been taking it. What did you eGFR reading say on your recent blood test results or creatinine levels?

primordial_soup's picture

my creatinine and eGFR have been bad for a long time now, way before i started mtren, and i am following up on it with a nephrologist. but my hemoglobin has only taken a dip recently after starting the Mtren.

it was 14.5 and then now 13.8 which was very surprising to me because usually i need to remove blood monthly for polycthemia and its already been 7 weeks now since my last blood donation.

so its very strange that my hemoglobin hasnt gone up again after 7 weeks.

and i do take vitamins that contain folate and b12, but most of my iron i get from eating red meat a few times a week.

so its possible the metribolone has shut down my natural production and this explains the depression and low hemoglobin

press1's picture

Ohh Mate - PLEASE, PLEASE PLEASE STOP doing this!!

If you already have bad kidneys and are seeing a nephrologist you have no idea the further damage you are causing to yourself with that Mtren - the best thing you can do is burn it or throw it in the bin bro. Its also likely to do with the Mtren that your depression is getting worse, you may get a momentary boost from extra androgens in your system but the crash back down is so huge because it is so strong that you are basically experiencing a comedown from it. Can @chad P or anyone else that knows a lot about kidneys please chime in here also.

Chad P's picture

While both NAC (N-acetylcysteine) and glutathione are antioxidants, NAC is a precursor to glutathione, meaning it helps the body produce glutathione, while glutathione itself acts as a direct antioxidant, protecting cells from oxidative stress and promoting detoxification.
Glutathione and Kidney Function:
Natural Antioxidant:
Glutathione is a naturally occurring antioxidant in the body, playing a role in protecting cells from damage caused by free radicals.
Kidney's Role:
The kidneys are highly dependent on an adequate supply of glutathione to maintain normal function, and glutathione has a rapid turnover in kidney tubule cells.
Oxidative Stress:
In conditions like acute kidney injury (AKI) and chronic kidney disease (CKD), oxidative stress can contribute to kidney damage.
Potential Benefits:
Some research suggests that glutathione may help control inflammation, reduce reactive oxygen species accumulation, and lower oxidative stress in kidney tissues.

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Chad P's picture

Effects of Resveratrol on Kidneys
Resveratrol, a polyphenol found in grapes, berries, and peanuts, has been studied for its potential effects on kidney health.
Potential Benefits:
Antioxidant properties:
Resveratrol may protect kidney cells from oxidative damage caused by free radicals.
Anti-inflammatory effects:
It may reduce inflammation in the kidneys, which can lead to kidney disease.
Improved kidney function:
Studies in animals and cell cultures have shown that resveratrol may improve kidney function by enhancing antioxidant activity, reducing inflammation, and protecting against kidney injury.
Delayed progression of kidney disease:
Some evidence suggests that resveratrol may slow down the progression of kidney diseases, such as polycystic kidney disease.
The resveratrol supplementation may have a potential renal protective effect in adults, by improving BUN, creatinine, and GFR levels. BUN, blood urea nitrogen; GFR, glomerular filtration rate; RCT, randomized controlled trial.

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SimonM84's picture

I caught you Press!!!! You’re a Sabrina Carpenter fan boy

https://m.youtube.com/watch?v=lqGg3fj7rWY

press1's picture

LMAO I'm more of an 'SOS Please someone help me guy ....

https://www.youtube.com/watch?v=IXmF4GbA86E

primordial_soup's picture

"Have you tried some of the better rated ones such as Lexapro, Zoloft or Citalopram?"
yes i dont like SSRIs

Wellbutrin has worked well in the past the problem is just that it needs to be taken twice a day since it wears off in the evening.

i think i might try bumping it up to 450mg/day like i took in the past because i think it helped a lot in the past

I haven't responded to people because I had an overwhelming incident yesterday and ended up taking like 5mg of metribolone all at once, my mood improved almost instantaneously and I felt better for the next 12 hours until the drug was out of my system again and I felt bad again.

None of this is typical of me to have emotional problems but it may be a part of the progression of my neurological disorder, that I've become depressed.

After taking the 5mg of metribolone my muscles became super hard and seemed to bulge outwards a little and I felt extremely mentally stable and not angry at all, I just felt more friendly and sociable and ended up having extensive conversations with other people that went really well.

Usually, I dont talk much with other people but when I was on the metribolone I felt better and socialization came naturally tbh I felt less angry than I usually am?

It could be that I just have a high tolerance for substances because I also dont get drunk easily like other people and seem to maintain self-control under the influence of substances.

press1's picture

The problem is buddy is that you cannot rely on metribolone when you are feeling bad, I understand it may make you feel better but the drug in itself is extremely bad for you - I cannot get that across enough. Its one of the most damaging oral steroids there is, even 1mg is a strong dose so taking 5 times this amount is going to land you in hospital mate sooner or later if you keep doing it. It is very damaging to the liver and kidneys, you could end up with irreversible liver damage or in kidney failure mate and that will be a lot worse than what you are having to go through right now. I am not just saying this to you to be a killjoy, I want the best for you. If you did better on the higher dose of wellbutrin then maybe thats what you should do, but taking mtren isn't the answer. Whatever you decide on doing - I would advise you buy some TUDCA and Astragalus Root online to take which will help your liver and kidneys. These will help also when you take the wellbutrin, if your liver and kidneys are in better health then you will feel more positive in yourself I think. If they become damaged then you will feel ill and have no appetite.

primordial_soup's picture

yeah im taking NAC i actually took like 5000mg of NAC yesterday after reading i should take 70mg/kg body weight

press1's picture

I would prefer you took those 2 supplements there buddy, they will help you more than NAC will. NAC works well alongside other supps but shouldn't be used just by itself, its mainly geared towards paracetamol overdose when you are admitted to hospital.

smurfdude1234567's picture

All SSRIms made me worse and suicidal when I never was before. I have tried everything listen except Citalopram.

Getting sober was the real answer. Absolutely nothing except supplements, clean diet, therapy, and stayed hydrated. Mental meds can be such a up and down.

Remeron was mild but still made me feel weird. It works for some. Trazadone, clonidine, and seroquel are all great for short term anxiety and sleep without being narcotics. Easy to get prescribed too, or find online.

Of course some of these meds work for others and he will have to experiment, but we can all agree that tren therapy is NOT THE ANSWER!!!

Pandateston's picture

The question is, have you looked for other compounds, natural or synthetic, mitochondrial supports and adaptogens that can help you in this process? Many times a simple stack can get you out of this limbo. There are many nootropics, meds, and studies out there. Certainly, Tren and Letro would not be the best long-term option, for you to keep cruising, I mean, the harm of neurological deterioration in the long term will be more than the immediate benefit. I understand that depending on the disorder and the situation, Trenbolone can have its place, I know a captain of the special forces in South America , who cannot perform his job perfectly and “calmly” if he is not under the effect of Tren, he needs that drive and aggressiveness to go up the hill in the Favela and get done what needs to be done with the drug dealers, cartels, deep shit. This is a very specific situation where the guy I'm talking about needs certain types of additives to stay active and productive, and he certainly won't be able to stay well for long due to the deleterious effects of it. If you require something very neurodegenerative to assist you with something in a neurological sector, something is wrong. I mean its a completely different scenario, expose yourself on certain dosages during blast for 12-16-X weeks vs expose yourself to the drug for an indefinite period of time, aiming only for the short-term benefits. Which one can cause more harm?! I would think it best if you rethink your protocol, but each person is different and free to make their own decisions.

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Pumped_'s picture

Why do want to take so much letrozole? On such low dose testosterone?

Engineereddisaster's picture

Yeah bro. I too have to take Tren for mood, especially when I’m actively killing hookers. It just helps me make sense of why I do what I do. Sometimes my mind plays tricks on me and makes me think I’m not making a difference in the world by eradicating these evil women…but when I’m on the Tren train all of my personalities are on board.

FiveFingerDeathPunch1's picture

LOL bro I spit my coffee into my windshield laughing so hard ! The laugh alone was well worth the $25.00 car wash every day penny

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primordial_soup's picture

really? because i took 5-6mg of metribolone yesterday and i dindnt feel any anger at all i just felt asertive, charismatic, confident and friendly in my interactions with others.. i think it just improved my interactions with others around me.

Chad P's picture

My guess is that’s pretty close to your normal nature. Im like you, I’ve never experienced the demon inside from Tren like most ppl claim. I think a lot of it is ppl that have never even touched it and go with that rhetoric, it’s like guys that act up when they’re boozed up are probably assholes when they aren’t.

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Mikeyt84LINY's picture

Omg this is classic.
Sounds about right to me though. Lmaoooo

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Jockstrap's picture
Black90tsi's picture

More drugs probably isn't the best long term solution to your issues. You need to find out what actually causing you to feel the way you do and address those things. Go find yourself a good therapist who can give you an outside view of what's going on with you and your feelings. Also start meditating daily. Go on YouTube and find some guided meditations to start. I actually prefer guided meditation using binaural beats. You would be surprised the effects mediation can have on your mental state after just a couple months.

Lay off the drugs and get help to find the actual issues. More things that will fuck with your hormones and mental state are just going to get you even more twisted up in the long run.

Codyw1771's picture

I was taking well Wellbutrin 300mg for the past 2 years. I just finally kicked it last month. Best choice I ever made. That shit is is as unsustainable in the long run.

White Bolt's picture

It seems to me your mind is turning to mush with the sheer abundance of bullshit you’re taking across the SSRIs, anabolic steroids, SARMS, and peptides.

It would be in your best interest to come off of everything, except a TRT level dose of test (125mg/w) and let your body gain some sort of homeostasis.

Spool's picture

Wellbutrin is going to drag you down and keep you low. Those antidepressants will fucking make you miserable in the long term once it has built up and stabilized in the system.

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press1's picture

Buddy, please don't do this. I know we have spoken at length about your condition over the years and this is definitely not the way to go about it - running trenbolone to try and feel better.

I am not sure about the long term effects of using Proviron to counteract your depression, but for sure it is a much better option than running trenbolone. I think you may be misinterpreting the way that tren acts on the brain and thinking its making you feel better when in fact I think it will be just making your thought processes act in a different manner. Trenbolone bypasses the frontal cortex effectively numbing it which is why you have less fear of consequences from your actions, so it may be just making you less aware of how you are feeling in general. Hopefully some other guys who use Mesterolone long term and consistently can chime in here and offer some help on how viable it is to run it long term. I would of thought running Test by itself would make you feel better just by itself?

It also concerns me a little that you may be totally tanking your oestrogen levels by running Letrozole, Masteron and Proviron and maybe this is partly to blame.

Mikeyt84LINY's picture

I've been taking proviron since August and i noticed it helped my mood and sense of wellbeing in the first couple of days. I've been taking 25mg daily with Lil bumps up to 50mg. I took a few days off here and there also just to try and not be so used to it cuz i don't notice the feel good effects and sense of wellbeing. One thing it never stops helping though is in the erection dept. I did take one 2 week break and wasn't running any mast or heavy dht. And my libido and erection started to flop literally. Good thing about is doesn't matter what i take tren anything whatever, that might usually mess me up in that dept. Doesn't have that effect while using the Proviron even at 25mg daily.

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Jockstrap's picture

Thats poorly thought out and looks like a feeble attempt to troll. You can do better

Mac12769's picture

Right. Lots of questions with no background info. No baseline lab work info. Shooting dosages in the dark.

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Jockstrap's picture

Im lost in his other forums as well. Maybe i need coffee.