posted Wed, 10/04/2023 - 04:41
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Is there any truth to the type of carrier oil changing the half life of the product?
I see many people love MCT vs. Other Oils but is there any truth to the type of carrier oil changing the half life of the product? Ofcourse the viscosity is different but what about half life? I have seen a few people mention it but nothing substantial or any real sustantial tests done to say yea! or ney!
Example:
Test C in Castor Oil
vs.
Test C in MCT Oil
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Long time old post --
Waking the Dead on a Question
This day error of Testosterone Brands
Witch brands use Castrol oil ?
I’ve tried everything I’ve read about to avoid Pip and still no relief. The only thing I can think of is that I may have an issue with the carrier oils. I’ve heard good things about mct oils as opposed to grapeseed, cottonseed etc. Does anyone have a recommendation for where to get products that utilize mct oils? And what brand and type of test to acquire? I Appreciate any help getting products with mct oils. I typically go to osgear.
Personally MCT works better for me. Thin oil and easy to go in
Everything you need to know about oil carriers can be found in these posts. It also explains why people using certain carrier oils get massive pip and a lot of irritation, also as of late mct oil is the preferred carrier alongside grape seed oil due to its very low irritant and its anti bacterial properties. my TRT carrier is gso unless I switch to another pharmacy and it ends up being mct. I have not had pip in over a year now since changing to a new provider. my new protocol is 100mg every 7 days.
https://www.scienceandhumans.com/testosterone-cypionate-versus-testoster...
https://old.medicalhealthinstitute.com/best-oils-to-use-when-injecting-t...
https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=6909596e-...
https://www.sciencedirect.com/science/article/pii/S0928098722001385
Knowledge is power. Happy reading.
I dont know if it changes the half life, once the compound is absorbed it does its thing. i think a carrier oil can effect the time frame that it takes to get absorbed into the body, same with where you inject and how much you inject. A larger amount, think big oil bubble, will take longer to be absorbed. Then there's sub-q vs IM injections, absorption into fat vs muscle.
MCT always worked best, however there are tricks of the trade when brewing, how is no one saying anything about the quality of R*ws? GSO I would say would be 2nd best in my experience. Also higher mg means different carriers also due to the break down your body has to do.
'm new ...how are u @Pmob....l was with monster gear l got bad reaction from their products because they uses gso.....mct same to work great...so do iron lion uses mct?
Why would we worry about raw quality if all the posted by source janos tests show superior quality? And purity close to or better than pharma?
According to Bayer, castor oil does increase the half life of Testosterone Undecanoate quite a bit, which is why they use it for Nebido with low solvents.
I read some studies on it years back and I'm sure you can find them easily, just search for testosterone undecanoate cast oil half life ncbi.
Indeed. I use Test U every 10 days for TRT. I’ve paid stupid money for a large amount of CENSORED years ago. I now use a (tested) UGL that supplies Test U in MCT oil. By day 10 (trough) reading I was still in the 700-800 range with CENSORED, with MCT oil it was around high 500-600s. I now inject once a week instead of every 10 days. I know a few UGLs now have been making test U in GSO and CSO, wish someone would just do castor oil.
Yeah but Delete that comment cuz we aren't aloud to name sources in comments.
There is a source that does castor oil for their test u. And they are a very good source, highly rated too.
So you just basically solved this whole thing with first hand experience using both Test U in Castor oil and Mct oil. You state by day 10 your bloods show a difference of 200ng/dL. Bloods don't lie. I assume that UGL's Test U was dosed correctly. Thanks for this valuable info brother. +1 @FlemDaddyKush @Makwa
No problem brother. It sucks because I’m prescribed Hikma test c. My endo said he can supply me with AVEED (USA version of Nebido) but I’d have to go to his office and get the full 4ml shot at once. He won’t let me have the vial to dose every 10 days lol.
Yes I HPLCd his product. He’s not a source here.
Well I remembered that you tend to lab test alot of gear so that makes sense.
https://pubmed.ncbi.nlm.nih.gov/10229906/
That study shows that test u in castor oil has a longer half life vs test u in tea seed oil
I feel the same things when i use pharma grade with castor oil test E vs UG MCT test E.
We have a study along with Sierra's bloods and personal experience.
There’s really no argument here. I’ll take actual clinical studies over the “bro trust me I’ve been doing steroids for years, I’m an expert”.
Lol absolutely no argument at all. Evidence is evidence. Tell you what you made this whole thing alot easier to figure out. I felt a slight difference but that wasn't solid enough for me to go on but this info is enough for me. Good discussion though.
So absorption kinetics are affected by the viscosity of the oily vehicle, concentration in the ester, (the higher the driving diffusion force for release), the volume of the product, and the site of injection.
This was commented by @Serrajitsu0876. I do remember seeing something similar to this long ago.
I commented on ester, inject location and viscosity of oil earlier. Thanks Serra
+1 @TheIcon hey man I liked the Scot Steiner reference as well as this post. Even though guys may disagree no one here is for certain lol. Only a lab test would know answer. But what was your opinion? Maybe I looked over it. What do you think? You must have an opinion
Thanks. I was on the Ester side then after reading some of the other comments it made me question it a bit more. To be honest I don't know anymore. I feel there is something to the oil which is used. Maybe not major but I could see it effecting the product. Like you said the only real way is blood test and multiple blood tests which none of us would do enough to gather the info required. Maybe one day we will be able to test our blood at home daily. Guess Theranos didn't work out haha
Well this post got guys thinking and some even losing sleep haha. Nah I like seeing different thoughts being commented. I just know my experience. Guess its just like the old test E vs C debate.
Same goes for the IM and SubC debate.
(26). The duration of action was 104 days for the SC and 101 days for the IM route. Serum testosterone concentrations (
Fig. 6A) did not differ according to route of administration after adjustment for age, body mass index, and clinical diagnosis (26)
There is a big difference in the bloodwork of subQ injections - Hematocrit is much less pronounced, where it spikes with IM injections. Because of this, it makes sense that the carrier oil viscosity and type could have an effect.
This is something I wouldn't bother concerning yourself with at all, choose the carrier oil that you feel healthiest on and well/clear headed. That will make a bigger difference as to how you feel throughout the cycle more than if a certain carrier oil shortens a compound by half a day or so. Case in point - I've tried many Test props over the 9 years I have run steroids and I never notice which ones seem to clear quicker than others, its just not something you notice. What I can tell the difference on is which come into play quicker than others, some will take 6 hours and some take up to 12. Even then though when comparing say MCT, GSO, Miglyol, Sesame seed etc there is no consistency to it. It leads me to believe that the actual RAW compound can vary more in activity time than the carrier oil, as effectively they are all propionate estered so should all behave in the same way - but they don't.
Gso or bust.
I'm with ya.
So there has always been a debate about this issue. In my opinion I do think that a carrier oil can affect the breakdown time of an oil, hence the slower or more sustained the breakdown of oil, the increase in half life to an extent. Both myself and
@Lil-Beirut both seem to notice a small difference. We both prefer GSO not MCT oil. Like explained below MCT oil dissipates the fastest leaving the hormone which is sometimes crystallized therefore causing pip, so that's what @Makwa was explaining. An oil like say GSO or a thicker oil will indeed remain a little longer acting as a buffer like Makwa said. Someone mentioned castor oil too, well there's a reason why pharmaceutical companies use it with the long acting Undecanoate ester. Long ester that's supported by a thicker oil makes longer half life. Now I see Test U in Mct oil which is a bit strange. I'd like to know the true difference between both in half life. Both are undecanoate.
My memory is fuzzy so anyone please correct me but esters are broken down by esterase enzyme and fats by lipase enzyme. In order for the oil depot to be broken down completely the lipase brakes down the oil while the ester enzyme cleave the ester leaving the base hormone to be used by the body. Just a simple explanation as I'm no expert though. But in my opinion I do feel a slight difference in longevity, with MCT oil lasting the shortest time. But maybe one of you geeks can explain this better to me lol.
I definitely notice it. Obviously we all know ester dictates release... No shit everyone has the experience. But carrier oil plays a part in my opinion.
You are correct.
I just have to agree with you and I figured you'd comment about your experience so thanks. Tell you what..I have some test e from a former #1 domestic that's no longer around. It's 300mg/ml and it hits hard and has a more sustained release! I mean it's one of my best ever. I gotta have GSO but I'll make due with mct oil. The thinness is a plus.
That reminds me of the old days... I'll be saving up for when someone can put stuff like that back on the menu.
I don't care what anyone says nothing beats ole school. Gym, bodybuilding, juice or what have you. Heck even music and movies. I can go on and on so I understand your pain lol.
I guarantee an src is reading this post and will be on it first thing in the morning!
I hope you're right...
Haha I'm looking at him right now at bottom of my screen. He's following this post!
I'm not buying it. Anecdotal, bioscience or placebo. It's not like the oil is buffering the ester. I'd need to see some lab work that would prove such an assertion.
My be the MCT is providing more energy then the GSO…… lol there for the placebo is kicking in……
Firm believer here. There was a Slavic source that was popular here and known to have the "goop". I think it was cotton seed or castor. But I only needed NPP 2x a week. MCT oil I feel the rise and crash of the compound way faster. Seems in and out like I need more frequent pinning.
It's physics in my opinion. When I would inject that stuff I would have a painless knot, and I know that goop was just chillin there. I'd massage that bitch out in the shower sometimes so it makes sense that it can slow things down just enough.
Put it this way... my stockpile has came to a complete halt because I can't find GSO or CSO. I keep getting stuck with MCT.
If you need a source that has gso I can point you.in the right direction, they offer every oil in mct or gso I've never used the source but they have a lot of good feedback.
Bro, I've bought some that says GSO on the label bro! Check my pics... when I got it in the mail it was in MCT. I hit up the supplier and they told me that the labs are always switching the carrier oil around without telling them.
The best half assed answer I ever got was that there's a shortage of medical grade sterile grapeseed oil since covid.
I know some brands that have done that. But this place isn't doing that. People would of complained by now. He specifically makes every compound in mct and gso so you can choose which you want.
I thought he got 86'd? Sending you a pm
Point us both in the right direction.
As long as they are credible
there would be no need for esters if we could control release rate by the carrier oil
I don't think the argument was that carrier oil dictates over the Ester but more so effects it in a way that the half life might not be 8 days it might be 6 now die to oil. The largest topic I found was actually on a "trans" board lol
I agree. My thinking was it supports the ester. Lol it's NOT the ester.
that's true but I do think an oils viscosity can't be ignored. A comprehensive lab study, that's where answer would ultimately lie.