Righthook's picture
Righthook
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+ 6 Mid-cycle bloods. 600mg/w SIS test E

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Am unable to post up more than 1 pic from my phone (is this normal?)

Test 295.3 nmol/l
E2. 107.5 pg/ml
SHBG 34.4 nmol/l
Albumin 48.9 g/l

Running these numbers through a calculator on nebido.com I get

Free test 9.99 nmol/l 3.38%
Bio available 265 nmol/l 89.7%

Have also been on Zydex Provi at 50mg day
Just finished week 6
Happy with test levels, E2 needs attention. Provi doesn't appear to be working as expected, not a lot of love for Zydex.
SIS labs now have a regular customer though.
Thank you 101.fitness

GrowMore's picture

Thanks for uploading this mate. Sending you a message.

Owes a Review × 1
giardap's picture

Provi doesnt lower shbg, it binds to it.
High SHBG occurs in high estro conditions and also others like high cortisol
If you dont know your pre cycle base levels for these hormones you have nothing to guide you other than current bloods and therefore cannot assume anything about the provi.

If you keep the exog test high and lower estro, you will lower shbg. Control your cortisol too, make sure you limit stress and anxiety, and dont eat coffee/stims, particularly in the am

You cannot make any assumptions on your provi or the lab (Ive had good exp with the lab in past) and neither can anyone else here (how the hell would any of us know unless they got it tested?? - look at the evidence only, estro thru the roof!) -- Provi is an extremely weak steroid and only displays its benefits under the right conditions -- You don't seem to know how it works and your estro is out of control

Sis labs is a great lab in my experience so far, so the test will really help you lower the shbg as you get that estro in check, and check cortisol. As your estro comes down, free test will rise as will TT. You might then notice the effects of provi (presuming you can distinguish it from whatever else you stack, most people cannot) on compounding the lowering effect of your ai, maybe a bit of fat loss and definitely taking shbg out of the equation somewhat to bump that free test up and lets face it... free test is what its all about

+1 for bloods

Righthook's picture

Thanks for this, really helpful. You're probably right about my lack of understanding about the Provi but it's not for lack of trying. For your reference I've just dug out my pre-cycle bloods
Test 18.91
SHBG 47.1
E2 22.9

my SHBG was higher pre-cycle.
Is it possible that by the Provi binding to the SHBG, only the "unbound" SHBG will show up in the test, meaning then that my Provi is working well. Or am I now talking absolute bollocks?

giardap's picture

I hear you man, there is a hell of a lot of misinformation out there and usually from well meaning sources.
This is great that you have pre cycle too, brilliant.

Nah you are definitely not talking bollocks mate, but the provi wont hide it as such, it just prevents it from binding elsewhere, so it is still measurable it also binds to albumin too, so the tests you are getting done are gold because they show free test and bioavailable test which contains albumin as well. See, the misconception comes from people using terms like lowering, versus binding. I am not surprised to see SHBG higher pre-cycle as the introduction of AAS on cycle will drive up test which can lower shbg. Most things that influence SHBG are lifestyle oriented, vitamins/minerals like zinc, script drugs, diet... for example, if you did a cut or mini cut before cycling, then it would raise shbg. As you are in range the number definitely is not worrying.

But re: provi effectiveness, free/bioavailable test is the real measurement. Lets say you have bloods from week 5 where you weren't using proviron, for arguments sake, and then began using it for a week and took another test, you would expect to see a jump in free test and bioavail test as the provi should be bound to shbg and albumin to allow more test to roam around and help you smash up the gym.

But... a lot of people do not use proviron effectively and as you stated previously UGL's cannot be always trusted and may be underdosed (zydex unliklely to be bunk unless is a fake, in which case check with zydex if contactable to see if your source is official etc.).

So what doses and admin schedule is where I would look next... provi must be taken every 4 hours, you can split your dose, but remember, as its out of the system so fast the effective serum levels are lower. So a 50mg dose isn't necessarily all it is cracked up to be. In my experience 150 split in 3 doses per day is where the rubber meets the road. But... I am not recommending that, just my experience.

When are you taking it, frequency and timing etc?

robb's picture

Very good results for sis test E.

In a promo × 1
SenseiMiagi's picture

Provi doesnt necessarily lower estrogen, so dont use that as only indicator of bunkness.

Righthook's picture

No, I understand, this wasn't what I was basing my assumption on, but my SHBG should be lower allowing for higher free test levels right?

giardap's picture

nope, not necessarily
where did shbg start from, what was the baseline etc.

SenseiMiagi's picture

Yeah good point. I looked over that. In that regard I would agree the Provi isnt doing what its intended.

tomos2big's picture

Everything ive used of zydex has been either complete crap or severly underdoesed never again would i risk that lab

Righthook's picture

Agreed mate, once bitten twice shy. I'll not use anything from them again