Billy Goat's picture
Billy Goat
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LabCorp blood test showing high e2 while on Tren

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Blood test shows e2 at 1107 while only running Tren E 700mg/wk Tren A 350mg/wk EQ 525mg/wk and Mast E 525mg/wk. Had not injected any test for 5 weeks prior to this test.

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Doss's picture

i'm overly curious to know why you stopped pinning test

Billy Goat's picture

If you scroll down to the bottom of this thread, I explain it. It's mostly been an experiment, as I see a lot of guys do it over on GH15.org, and many european and middle eastern bodybuilders do it, as well. Since I've been using gear for 26 years, I don't come off anymore, so it gives me a chance to experiment with different protocols and gear, without worrying about PCT and getting boners. To be honest, I really haven't seen a difference between running a trt dose, and not running any test at all. Having test as a base is essential when you run cycles, or you're just starting out, and you need to learn how you respond to gear. But otherwise, it's not absolutely necessary. A lot of middle eastern bodybuilders use EQ as a base, and you see how dry and hard they are. I'm on test now, but I'll be dropping it again sometime this week.

Doss's picture

Gotcha. I actually had read down the thread beforehand, but must've somehow missed it.

I agree with you about not being able to tell the difference between trt dose and no dose. Because of this, I cruise at a steady 250/wk between and during cycles. Only time I go above is if I'm trying to bulk or running a test only blast.

MegaT883's picture

If you just come to the party I started a thread about Labcorp blood tests giving high estrodial reading while on Tren. Billygoat posted up about his experience and I asked him to post up his Labs and here they are so thanks Billygoat.
http://www.eroids.com/forum/general/general-talk/tren-causing-bogus-elev...

Even though Mast has a reputation like Proviron as anti E it sure didn"t seem to help this stack. But then again I just don't think the E2 test is reading correctly. The only thing I see in this stack that converts as you know is 525mgs of EQ. Makes you want to scratch your head and say WTF, are these numbers for real.

humpnpump's picture

So according to the Vewi theory the tren eats the fat and leaves excess E2 behind which is a plausible explaination. He mentioned proviron to help with the E2 levels in the blood, what does proviron do to excrete e2 out of the blood and body.

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MegaT883's picture

What J223 is telling you is fact.It binds strongly to aromatase more so then Testosterone.Which prevents
testosterone from interacting with aromatase and converting to estradiol. There are only 2 ways estradiol is made in man and both involve aromatase, androstenedione to estrone(E1)(E1 can convert to E2) and testosterone to estradiol(E2)
It not only binds to SHBG but to Albumin also. On average 98% of serum Test is bound to these 2. What that means is it increases Free Test which is what interacts with AR. It is Free Test that makes you feel good. Serum Test doesn't do anything it's the Free Test that does.

humpnpump's picture

I know what proviron is for in freeing up Test and blocking SHBG, but that's not the question Mega, when tren breaks down fat and estradiol is left behind, that not by the way of aromatase, so what is the proviron doing to lower the estradiol levels in the blood since estradiol has already been produced.

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Doss's picture

this tren/fat/estro theory is new to me, but has me intrigued.

as far as the roles proviron plays here, simply put:

the newly released fatty acids and triglycerides become engaged in the various metabolic pathways for energy production; otherwise, they would just be rebundled together and transported back to the addipose cells (fat cells) for storage. they are only used to energy purposes, and not rendered as precursors or raw materials for estrogen synthesis.

however, a chain reaction may take place, according to Vewi's theory, that causes an influx/elevation of the hormone. back to the basics here, however, tells us that the aromatase enzyme remains in the picture to synthesize the hormone in response to whatever stimulus.

proviron helps by lending it's anti-estro properties to offset some of the enzymes' conversion/binding.

MegaT883's picture

The answer is nothing. The only thing proviron does is in helping to keep estradiol from forming to begin with period. Once estradiol is formed it's there and proviron has no major effect.

j223's picture

Wrong.

Because once testosterone is freed from shbg it can convert to estrogen or DHT. Since proviron is bound to aromatase enzyme this leave it to convert to DHT. Once it is DHT it can lower estrogen

MegaT883's picture

Here's the point I'm making no matter what you take estradiol is not lowering while on Tren. Take proviron,mast,ai,clomid, straight tren no Testosterone etc etc and on Tren bloods are showing estradiol elevated. Why? The only thing I can think of is that the numbers are not true.

j223's picture

Right the lab test is recognizing tren as an estrogen. Which is funny because tren is a progestin.

j223's picture

Because Proviron frees up test by lowering SHBG. It also binds to aromatase which means testosterone in your blood not converting to estrogen.

Remember testosterone converts to estrogen and DHT. When you add proviron testosterone converts to more dht and less estrogen. More dht = more estrogen suppression.

killroy's picture

I still have yet to see any scientific proof that when tren breaks down fat, estrogen is magically left behind at ridiculous levels. I find this theory a little nutty..

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Doss's picture

it could be possible. when learning about the various metabolic pathways and their roles in nutrition, the textbooks touched on how these pathways can affect different aspects of the endocrine system (hormones).
when one process affects another, hormones and neurotransmitters are inolved in the mix to provide communication between cells.

we could probably find some case studies on 'effects of metabolic oxidation on estrogen'

i like to use http://scholar.google.com/ for most of my research. it's another search engine, but the results are strictly scholarly articles.

j223's picture

Proviron binds to SHBG and Aromatase enzyme leaving more testosterone in your system and not getting converted to estrogen. Proviron is highly androgenic and DHT like effects. DHT is a natural estrogen regulator.

alain_305mia's picture

I hope you have an ai on hand...you need something to tear that estro down...plus your liver might not be doing to well.