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DC88
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Insulin response to protein vs glucose

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I always hear a lot of people saying that protein will raise your insulin just as high or higher than sugar. I'm a big fan of research (worked in a few research labs), and this is a pretty good study on the topic. Granted there was a small sample size, only 8 subjects, but the methodology was pretty good.

Abstract:
Eight normal subjects were given 50 g protein, 50 g glucose, or 50 g protein + 50 g glucose. Plasma glucose, insulin, C-peptide, glucagon, alpha-amino nitrogen (AAN), and nonesterified fatty acid (NEFA) responses were then determined over 4 h. Protein stimulated only a modest insulin rise and the area above fasting baseline was only 28% of that after glucose. The sum of the serum insulin area following protein ingestion and that following glucose ingestion was 100.4% of the combination meal. C-peptide changes confirmed the insulin response. The addition of glucose to the protein meal resulted in a 60 min delay in glucagon and AAN rise compared to the protein meal alone. Subsequently AAN and glucagon increased to levels greater than or equal to those observed after protein ingestion alone. In summary, protein is a much less potent secretagogue for insulin than is glucose in normal individuals, and the effect on insulin secretion is not synergistic. Addition of glucose to a protein meal results in a delayed rise in AAN and glucagon concentrations in normal subjects.

The study used 93.5% lean (6.5% fat) beef. The results demonstrated that 50g of beef protein led to an release of insulin that was less than 1/3 the level of insulin secreted in response to 50g of glucose. I'l include a link to the abstract and full text if anyone is interested. I thought the results were pretty interesting, and may be applicable to anyone dieting.

Abstract: http://www.ajcn.org/content/44/6/847.short

Full Text: http://www.ajcn.org/content/44/6/847.full.pdf+html

shrapnel's picture

Nice post! I wonder about this! Confirms what i already thought.

DC88's picture

Thanks man. Yeah it lends itself to how I can eat on DC training (3+ lbs of steak everyday) and not get super fat.

DC88's picture

Thanks man. Yeah it lends itself to how I can eat on DC training (3+ lbs of steak everyday) and not get super fat.