Being the big fan of aromasin that I am and getting sick of crashing my e2 by trying to run letro as my ai of choice on blasts I’ve been doing a little more research into it and I stumbled across some interesting information.

To start aromasin is kind on lipids, lowers SHGB, increases IGF-1 and doesn’t cause rebound like it’s friend Adex. All good stuff!

Now we’ve all read that aromasin’s half life is 9 hours which makes us believe that we would have to dose twice a day for stable blood levels. However aromasin is a suicidal aromatase inhibitor and when it enters the blood it binds to aromatase enzymes and destroys them (hence why it’s called suicidal). This means there’s a big reduction in your oestrogen levels for up to 72 hours after a single 25mg dose. Oestrogen levels only start to raise again when the body starts making new aromatase enzymes which were previously destroyed by aromasin according to this study which looks at the pharmacokinetics of Aromasin in men:

https://academic.oup.com/jcem/article/88/12/5951/2661508

A quote taken from it:

Maximal suppression of estradiol (62 ± 14%) was observed 12 h after a single 25-mg dose of exemestane. Estradiol remained suppressed by 58 ± 21% at 24 h and returned to baseline 3–6 d after treatment

In English I translated this as you can take aromasin EOD, E2D or even E3D and still maintain comfortable levels of oestrogen.

It also states that aromasin increases total testosterone in natural males by 60% after 10 days. But even cooler than that it increased free testosterone by 100%. Something to consider when going onto PCT with some HCG in the mix.

Thanks for reading.