posted Sun, 05/15/2022 - 15:10
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Anavar/Liver Supplements Female here
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Hi all !
I am hoping someone can clear it up for me and even shoot me some more knowledge here . I started a anavar cycle , 10 mg a day and i plan on going 6wks . My question is , can someone lead me in the right direction on the supplements to take with ? I keep reading diff stuff such as Milk thistle counteracts muscle gain etc etc . Also that it passes through the kidneys not the liver therefore no liver supplements are necessary. So i am confused and want to make sure i am doing this as healthy for my body as possible ! I know there are information gurus in here to help --
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TricepatopsMilk thistle is great for liver. I use it for every oral run and that is the only supplement and my liver values are always good.
I use Milk Thistle extract everyday and have done for quite a while now, it has many benefits including lowering cholesterol, helping the heart and helping promote muscle growth and reducing inflammation. I've never had it affect muscle growth or strength. Anavar tends to affect lipids more than it does the liver especially at the lower dose you are taking. Here is a good article on MT:
https://www.t-nation.com/supplements/news-milk-thistle-longevity-exercise/
RustyhookerIve taken bloods on milk thistle and saw palmetto during hard cycles and the numbers were excellent. I was really suprised. Psa was at bottom of norm even with saw paletto and ran mast etc really high.
Oh wow ! Great read !! Thank you !!! Can you recommend a dosage on the milk thistle ?
I've read a lot of articles on the dose and the general advice for protection against oral steroids (not just general liver health for the average person) is 300 to 400mg of EXTRACT per day, you can take this up to 3 times daily but I tend to just do the once. Where many go wrong is they look at the seed mg value which is generally 20 times higher than extract value. So where you see things like 2000mg per capsule just ignore that and look up what the extract value is. This generally ranges 100 to 300mg per capsule :-)
At the doses you are taking it is really not that big of a deal and I wouldn’t lose any sleep over it. Guys cranking 100mg/d, yeah they need to be more proactive with supps. With var I would be more concerned about cholesterol levels. May not be to hard on the liver but var will flip your cholesterol light a light switch. That would be the bigger issue for you. Keep up with your omegas/fish oil.
Okay see that is the stuff i need to hear ! I have been taking omega 3 twice daily as well as another fish oil serv and eating a diet that is more cholesterol friendly if you will . I am just un sure on if i need to take milk thistle or not . Any other supplements you think i should be taking on cycle ? I’ve also read that grapefruit juice w the var helps . Have you heard of that?
It's specifically white grapefruit juice that will increase the absorption/potency of any drug, but I don't recommend it. You must drink the juice (16-20oz) 45mins prior to taking an oral medication/or oral steroids and what it does is inhibits the CYP3A4 enzyme of the cytochrome P450 system in the intestinal mucosa, increasing the bioavailability of drugs with a high first pass metabolism. It will cause the drug to illicit more harm to your liver and body by doing this. If you're drinking regular ruby red grapefruit juice, you gotta drink like damn near the whole bottle, so calories wise isn't efficient, if you're trying to shred up with Var.
Grapefruit juice is supposed to help with bioavailabilty I believe. @Rustyhooker may know more about that. I wouldn't be to concerned about it though and would probably recommend against using it at this point. 10mg is a hefty dose for a female, especially if first run of it. I would start out at 5mg if personally recommended it to someone for first time. As far as what else to take with it, just eat a balanced diet and keep up with healthy fats. Nothing wrong with adding in a multi-vitamin or some NAC/milkthistle if you are losing sleep over your liver.
RustyhookerFaster uptake with grapefruit juice @Makwa. Theres warnings on slow/timed release medications aboyt it too. Interesting stuff
@Makwa they gotta be careful with grapefruit juice. And ole Rusty Hooker knows this. It pretty much deactivates an essential enzyme that's used for detoxification of drugs
Just safer not to mess around with grapefruit juice and orals.
100% agree
Rustyhookerhttps://www.nhs.uk/common-health-questions/medicines/does-grapefruit-aff...
Healthy person using just var winny tbol....yes...its speeding up intake. But the list above effects many of us. Medications taken and just part of being older can be effected
@Makwa Yea Ole Hooker Naringin is the flavonoid in grapefruit juice that's responsible for inhibition of CYP3A4 liver enzymes. Not good, not good
I use “Liver 52 DS” & “NAC”
After your cycle take 4/5 days off of training & go get bloods to check your liver enzymes. I always quit training a couple days before I do my blood test and it’s more accurate on the liver AST results.
TricepatopsAST isn't for just liver it is for heart muscle, kidneys and other organs. Also if you lift on a regular basis you shouldn't have high AST from muscle breakdown. Now say if you took a month off and went back that is where you AST will most likely be elevated. ALT is a better indicator of liver health though that isn't the whole picture. Also most of the time AST is elevated and ALT is normal it isn't the liver it is something else.
Living4ThePumpI can just repeat what I tell everyone who starts using PEDs. Keep your hands off of orals. This stuff messes up your liver and just your whole body. Stick with injectables and your body will thank you. Nothing that orals do better than injectables.
Start with a basic test only cycle and you will make huge progress if its your first cycle. Also, no need to just hammer away 500mg test per week. Start with 200mg and keep increasing to 250-300 after 8-12 weeks if blood looks good and you got no sides. You can repeat that until you start noticing estrogenic side effects, then scale back and hold. get bloods and see where you are. If everything is fine you can add in a compound that doesn't aromatize like primo.
In terms of liver the best you most likely can get is TUDCA. Other than that Supplement Needs has a product called Liver stack that is excellent.
I have to edit that i am a woman lmao sorry !