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+ 21 Everything you want and need to know about HGH


Hgh, A How To Use Article...
by Dr. G. Patino MD., HGH Medical Clinic Puerto Vallarta

** Hypopituitarism Diagnostic Tests


Human Growth Hormone (somatropin - also referred to as rHGH, hGH, or GH) is created by the pituitary gland, the primary form consisting of a 191 amino acid chain. When we are young, HGH is in big part responsible for the proper growth of bones, muscle, and other tissues. To little of this hormone and we remain dwarfs … too much and we become giants and/or suffer from abnormal growth deformities. As we become adults, hGH is responsible for keeping muscles from wasting away, supports healthy immune system response, regulates aspects of our metabolic function dealing with increased fat metabolism and healthy body composition in later life, and maintains and repairs our skin and other tissues.

The levels of hGH usually peak while we are in adolocence, then begin to taper off in our early 30s; thus by the time we reach or 60s our levels of hGH secretion produced daily is as low as 10% of what it was during our youth; and many of the age markers showing decreased hGH are listed below:

· Increase in fat.
· Decrease in muscle and lean body structures.
· Decreased skin texture resulting in a less youthful appearance.
· Decreased bone density, onset of osteoporosis.
· Decreased brain function, loss of intellect with aging.
· Decreased sex drive.
· Decrease in overall physical and mental well being.
· Increase in sleep disorders, lower quality of sleep.
· Depression and fatigue.

The addition of supplemental HGH beginning in the later 30’s can reverse or improve these symptoms in the majority of people attempting therapy. This is why you will often hear references with respect to HGH as “the fountain of youth” and other similar terms. It can present a better quality of life for those aging as well as provide some great benefits for bodybuilders.

For bodybuilders, HGH (and the IGF-1 that is a result of its use) is the only substance that can actually initiate hyperplasia, which in the interest of our use in bodybuilding equates to new muscle cells. While use of anabolic steroids can cause hypertrophy (the enlargement of existing muscle cells), steroids do not offer the ability to recruit and mature more muscle cells. HGH can. HGH also increases protein synthesis, which can be responsible for hypertrophy. HGH also strengthens and heals connective tissues, cartilage, and tendons. These uses are what make it so attractive to athletes in all sports, and in bodybuilding in particular.


First be advised that the only true form of hGH comes in the form of a lyophilized powder, any other form that you see advertised or offered is NOT true hGH. The only way to administer true HGH is by subcutaneous or intra-muscular injection.

hGH is fragile and needs to be protected from both the light and the heat. hGH should be stored in a cool fridge 36 - 46 degrees Fahrenheit or 2-6 degrees Centigrade;before and after its reconstitution UNLESS... you are using the product JTPN or SAIZEN. Almost all brands of somatropin (hGh) need to be stored, shipped and remain in a refridgerated location. There only two brands (that I know of) that can survive normal room temperature during storage and shipping; however only before mixture or reconstitution. ALL BRANDS need to be refridgerated after being reconstituted (mixing the lyophilized poweder and the bacteriostatic water).


Your vial of hGH (either JTPN, SAIZEN, SEROSTIM, CRYOTROPIN, GENTROPIN, JINOTROPIN, NORDITROPIN etc..) comes in the form of a lyophilized powder and has an extra small bottle of bacteriostatic water for mixing. The amount of the powder should be indicated on the vial, it will stated Units (IU's) or Milligrams (mg). If in milligrams the conversion is precisely 1mg=2.7IU but they state in general that 1mg = 3IU's so 4IU's equal 1.33mg. As a physician I use the precise measurement but most people use the 1mg = 3IU's since that is the standard commonly referenced by mfg.

We will add the bacteriostatic water (or sterile water) to the lyophilized powder {some patients and physicians I’ve spoken with during my experience of 20years on this product use liquid vitamin B12 to reconstitute} and thus prepare for injection.

What you choose to reconstitute hGH with depends on how rapidly we use the GH. Bacteriostatic water is basically sterile water with 0.9% Benzyl Alcohol added, and this Alcohol keeps anything from growing in the water, thus making it safe for injection for the longest amount of time, about three to three 1/2 weeks. If the amount of GH in our vial is enough to last for a few weeks at our desired daily dosage then bacteriostatic water is the way to go and diluent of choice. Many users {bodybuilding use about 2-5 IU's a day} and remember most vials will be used up long before any bacteria begins to grow in the reconstituted hGH. So it's really a personal preference which diluent you use.


1.) Take some alcohol and swab the stopper {top of the vial} of your hGH vial and the diluentwater.

2.) Take a 3cc syringe with a 23 or 25 gauge needle (1" or 1.5") and draw up the amount of your preferred dilutent. The amount isn't critical, other than making sure you know exactly how much you have used. The rule of thumb is choose an amount that will make measuring the final product easy
•Example: 1ml (cc) per 10IU vial of hGH means each 10 mark on U100 syringe equals 1 IU of HGH
•2ml (cc) added to a 10 IU vial of HGH means each 20 mark on a U100 syringe equal 1 IU of HGH
•3ml (cc) added to a 10 IU vial of HGH means the 30 mark on U100 syringe would equal 1 IU of HGH

3.) Then you take the syringe {already having the dilutent} and push it into the vial contianing the lyophilized powder, you may want to angle it so that the needle touches the side of the vial, and avoiding injecting the diluent directly onto the lyophilized powder; you want to make it run slowly down the side of the vial (don't force it all at once or don't rush it in).

4.) After all the diluent has been added to the vial of hGH, gently swirl (do NOT agitate or violently shake the vial) until lyophilized powder has dissolved and you are left with a clear liquid. The hGH is now ready for use. Store your reconstituted hGH in the refrigerator and if you used bacteriostatic water to reconstitute, it will be good for about three weeks. If you used sterile water, then it will only be good for about 4 -5 days.


After you have reconstituted the hGH, you need to know how to measaure the amount for injection right? You need to use a U-100 Insulin Syringe to draw and inject the hGH. Here's how: since you know the amount of IU's in your HGH vial and you know how much water you have diluted it with, just divide as listed below: You need to know the following -
•1ml = 1cc = 100 IU's

So take the number of IU's of the hGH off of the label of the lyophilized powder (most common is 4 or 10 IU's) and divide that into the amount of diluent used.
We used 1cc or a ml of water; we also have a 10 IU vial of hGH.
Thus we know from above that 1cc = 100 IU's, so we have 100 IU's of water.
We now divide the 100 IU's (the amount of our water) by 10 IU's (the amount of hGH)
•100 IU / 10 IU = 10

This 10 will perfectly correspond with the markings on a U100 insulin syringe. In our example, every 10 mark on the syringe will equal 1 IU of hGH. You want to draw 2 IU's of GH? ....draw out to the 20 mark on the syringe.


1.) How much actual hGH you are dealing with (read the vial 4IU or 10IU?)
2.) How much water (dilutent) are you using to add to the hGH.
3.) Divide the amount of water in units by the amount of hGH in units.
4.) This result will equal the measurement on your U100 Insulin syringe per unit of GH.
5.) multiply the number you get {same as in step 4} by how many units you want to inject. This is the number to draw to on your syringe.

Now that we know what HGH is and how to reconstitute and measure it, lets look at some strategies for using it to our best advantag


There are many different approaches to taking HGH. The right approach for your particular situation will depend on your goals. For many, HGH is a general purpose supplement to help maintain low bodyfat percentages and reasonable levels of lean body mass. For others who have reached their genetic potential for growth, HGH is a supplement that can assist in continued growth beyond what mother nature gave you to work with. For yet others, it is a supplement that is used for general health and healing of injuries. Let’s look at each of these uses with respect to a reasonable HGH program.

To begin with, it should be stated that for the vast majority of HGH users, results are not rapid and earthshaking in nature. If your idea of using HGH is to get ripped in a few weeks, gaining 20 pounds of muscle in a matter of a month or two, or being miraculously healed in a matter of a few injections … you are likely in for a BIG disappointment. HGH does some pretty incredible things, but it HAS to be viewed as a long-term endeavor. A reasonable length HGH cycle would be 20-30 weeks in length. While you will always be able to find the one or two individuals who will make great strides in a short amount of time, the majority need to be dedicated to its use for the long haul for it to be a worthy venture.

As mentioned in our introduction to HGH, one of the major roles it plays in growth is by its passing through the liver, which in turn secretes IGF-1. This process is cumulative in nature, and it will take some time for your exogenous HGH use to bring your IGF-1 levels to create an environment conducive to optimal growth. While it is true that HGH begins shuttling nutrients to your muscles, and begins mobilizing fat from the first injection, these behind the scenes benefits will only be VISIBLE several weeks (up to 12) down the road.


For anti-aging, general health & healing, fat mobilization
For these purposes, a dose of 2-3 IU’s per day will be sufficient for the majority. A dose of 1.5 to 2.0 IU’s is considered to be a full replacement dose for those in their middle-age and beyond.

For gaining lean muscle and substantially improving body composition
For this purpose a dose of 4-8 IU’s per day will be necessary. Most people will respond very well at a dose of 4-5 IU's per day.
For maximum benefit in this regard, the addition of Testosterone, Insulin, and low-dose T3 would be something to seriously consider. More on this in our comparative cycle guide of HGH/Insulin/IGF-1.

Regardless of your goal, as a general rule the best way to begin your HGH program is to start with a low dose and ease your body into the higher doses. This will allow you to avoid or at least minimize many of the more common sides of HGH such as bloating and joint pain & swelling. Most people can tolerate up to approximately 2 IU’s with few sides, so that would be a good place to start.

For many using this as a general health supplement, that is as high as you will need to go. For others this will be only the start. Above 2.5 – 3 IU’s, I would definitely suggest that your split your injections into two per day instead of one unless it is just not feasible to do so.

Here is what a good ramp up program would look like:
Weeks 1-4 = HGH 2 IU’s one injection
Week 5 = HGH 2.5 IU’s one injection
Week 6 = HGH 3.0 IU’s split into two injections of 1.5 IU’s each
Week 7 = HGH 3.5 IU’s split into two injections of 1.75 IU’s each
And so forth until you reach your desired dose.

If at any point in this progression you begin to have unbearable bloating or joint pain, drop the dose by 25% and hold it at this lower dosage for a couple of weeks. If the sides subside, begin your progression back up toward your desired level. If the sides remain, lower your dose again and hold it at the lower level for two weeks before beginning the upward progression. This method will keep your HGH experience a good one and side free for the most part.

For a normal cycle of 5-8 months in length, injecting once or twice a day, 7 days a week should be fine. While there are studies that suggest that the suppression from exogenous HGH is short lived (about 4 hours from injection), there are no large-scale studies to indicate safety of everyday injections in long-term use. There are studies by anti-aging groups demonstrating that a day or two off per week is adequate to protect the pituitary and its triggers over long cycles. If your use of HGH becomes more a lifestyle than a single cycle, I would consider running it 5 on/2 off, or 6 on/ 1 off until such time as we have reliable data demonstrating long-term safety sans any degradation of your own output or the triggers initiating that output.

Another option would be to run your HGH cycle everyday for the first two months to get your IGF-1 levels elevated quickly and to a level to assist you in an anabolic way, then drop back to 5 days a week.


As described above, the body produces HGH is a pulsatile fashion throughout the day with the heaviest pulses occurring approximately 2-3 hours after going to bed as you fall into a deep sleep. Injectible HGH is completely absorbed and put to use within approximately 3 hours. The strategy with respect to timing depends somewhat on our age and the other elements of our cycle. As you will see below, there is no single best strategy … it depends a lot on your individual situation.

For those that are between their late 20’s and early 50’s, there is still a reasonable chance that your own endogenous production of HGH is still at a reasonable level. The best time to take and injection, this being the case, would be early morning …. After your body’s own release of HGH in the night. If you get up to go to the bathroom in the early morning, this is probably the perfect time to take a couple of units of HGH. This will be the least disruptive time to take an injection of HGH. The second best time would be first thing in the morning when you wake up

If you are splitting your doses, two times of the day when your cortisol levels are at peak are when you wake up and in the early afternoon. Another good strategy is to take your HGH injections at these times. Cortisol is very catabolic by nature and a well -timed HGH injection can go a long way toward blunting this effect.

If you are in your late 50’s or beyond, or if for some reason you have a condition that has rendered your pituitary incapable of a normal release of HGH, a great time to take HGH is right before bed. This allows you to closely mimic the natural pattern that would occur if your pituitary were functioning properly. For the rest of us, taking your HGH right before bed is going to end up creating a negative feedback loop, robbing you of your body’s own nightly pulse of HGH.

Yet another strategy should be considered if you are using insulin with your HGH. Insulin should be used immediately post workout. HGH and insulin do some great things together – they shuttle nutrients in a very complimentary way with each other, and the combination of HGH and Insulin create the best environment for IGF-1 production. If you are using insulin immediately post workout, this would be a great time to take a couple of units of HGH.


HGH as a Body Building Enhancement Drug
Human growth hormone (HGH) has been used by body builders for years to promote physical enhancement.

When a person's pituitary glands release human growth hormone, it causes their liver to release IGF-1. IGF-1 is at its highest in childhood, and, as a person ages, the level of HGH their body produces declines. Normally, after puberty, your body stops growing new muscle cells. The number of muscle cells you have for the rest of your life is genetic, and the most you can do is increase the size of these cells through weight training or steroids. However, by using HGH , you can actually grow new muscle cells. This allows you to reverse genetic dispositions and achieve an ideal muscle density.

Human growth hormone raises your energy level and metabolism, causing you to both feel more active and burn fat. In fact, the only weight that you will gain while taking HGH is weight from lean muscle. Unlike steroids, the weight gain from HGH is slow -- normal weight gain results are one to two pounds of lean muscle every two to three weeks. With steroids, you gain mostly water weight; with human growth hormone, you gain only lean muscle mass. Human growth hormone also forces your body to burn fat for energy. This means that body builders can eat a lot of food when necessary and not gain unwanted weight from fat.

As a body building drug, HGH increases lean body mass, shortens recovery time between workouts, and enhances overall performance with less risk of detection than other performance-enhancing drugs. HGH strengthens joints and ligaments and heals damaged tissue.

Other body building benefits of human growth hormone include increased protein synthesis abilities, an increase in the amount of insulin a person can use effectively, and an increase in the amount of anabolic steroids a person can use effectively.

One myth that surrounds the use of human growth hormone in body building is that it causes an extended belly. This is not actually caused by HGH itself; rather, it is caused too frequent doses at too high levels. Taking HGH as directed by your pharmaceutical supplier will not cause such disfigurement.

Human growth hormone increases strength, promotes healthy weight gain, promotes fat loss, and decreases muscle loss during off periods. The side effects of using HGH as a body building drug are minimal and rare. Users claim that they achieve desired results. HGH does not cause abnormal bone growth (Acromegalia). After a person's period of natural growth in childhood, the ends of their bones fuse and quit growing.

hGH - Treatment as a Weight Loss Drug:

Thousands of scientific studies and clinical trials have shown HGH supplementation to be remarkable in its effectiveness for weight loss. Physicians and health care professionals worldwide have conclusively determined HGH supplementation to be one of the most highly effective weight loss, body fat burning and lean muscle building methods known to science. If your goal is to once and for all rid your body of unwanted fat bodyweight, then start by coordinating your body's metabolism into an efficient fat burning machine by including HGH in your weight management program.

HGH is a natural substance that is excreted by the pituitary glands in the human body. As a person ages, the level of HGH that their body produces decreases. However, human growth hormone drugs work to raise a person's levels of HGH back to a youth-like level, therefore aiding in weight loss.

Human growth hormone works by increasing the amount of IGF-1 that a person's liver excretes. IGF-1 prevents insulin from transporting glucose to cells. Normally, after you eat, your pancreas releases the amount of insulin necessary to transform carbohydrates into glucose. Your body then stores this glucose in fat cells and uses it for energy. HGH induced IGF-1 prevents insulin from storing this glucose in cells, therefore forcing your body to burn fat for energy.

Normally, a person's body uses all of their glucose for energy before seeking that energy from their fat reserves. Human growth hormone forces your body to seek energy from the fat reserves first. This results in significant weight loss.

Because human growth hormone forces your body to burn fat for energy, it means that you will lose weight even in your inactive periods. Energy is required for all aspects of living. Therefore, HGH can force your body to burn fat while you are sleeping. Additionally, it allows you to eat large amounts of food without gaining excess unwanted weight. HGH replaces the need to diet.

Another beneficial effect of HGH is its ability to force your body to grow new muscle cells. Normally, a person stops growing muscle cells after puberty. They then have to do weight training in order to increase the size of these muscle cells. However, the number of muscle cells never grows.

Human growth hormone helps to increase the number of muscle cells a person has. This means that they have to do significantly less weight training in order to develop muscle density. HGH, in addition to helping you lose weight, can help you increase muscle density and develop definition. It will help you get the body you want in the areas of weight and muscle definition.

Another beneficial effect of human growth hormone is heightened energy levels and metabolism. Naturally produced HGH is responsible for these effects in children, and, by using human growth hormone drugs as an adult, you can feel the same energy as you did in your youth. An increased metabolism means increased fat loss. In fact, HGH can cause weight loss even without exercise.

Human growth hormone increases strength, promotes healthy weight gain, and promotes fat loss. The side effects of using HGH as a weight loss drug are minimal and rare.

hGH - Treatment for Anti Aging Therapy:

HGH Treatment as an Anti-Aging Drug
Human growth hormone (HGH) has been called a miracle anti-aging drug -- it's widely used in alternative clinics for the elderly as a means of rejuvenation. Human growth hormone is an effective anti-ageing drug due to its ability to return an adult's hormone levels to those of their youth.

HGH is a natural substance produced by one's pituitary glands at its highest levels during childhood. The higher levels of HGH in a person's body, the more IGF-1 their body produces. IGF-1 is responsible for both healing damaged cells and developing new ones. As a person ages, the amount of human growth hormone their body produces declines. This means that one's body is less able to repair their damaged cells. Cell damage is what causes aging

By taking human growth hormone, you can force your body to repair the damaged cells that cause it to age. Some of the most notable areas of ageing that can be reversed with HGH are discussed below:

Skin Damage:
The sun, UV rays, and cigarette smoke are all damaging to skin cells. Unfortunately, many of these environmental elements are unavoidable. Human growth hormone works to repair these damaged cells. The result is smoother, less-wrinkled skin.

Energy and sexual function increase
As a powerful aphrodisiac, HGH restores sexual potency and sexuality in men. Many of the women who use it also report increased libido, heightened pleasure and the equivalent of greater potency in men, which for the female is multiple orgasms. It also helps to alleviate menstrual and post-menopausal symptoms, and eliminate vaginal dryness. According to many of the physicians who use Growth Hormone in their practice, the sexual changes are striking, effecting both men and women.

Bone Deterioration:
A human's bones weaken with age. Age induced bone deterioration is the main cause of the detrimental bone fractures common to the

elderly population. Human growth hormone not only strengthens bones, it can even repair damaged bone cells. The represents a potential cure for the worst type of bone deterioration -- osteoporosis.

Memory Loss:
Damaged brain cells are responsible for memory loss and can lead to Alzheimer's disease. HGH works to heal damaged brain cells, preventing age-related mind deterioration.

Because of their ability to heal damaged cells, human growth hormone drugs are considered the most effective anti-aging drugs currently on the market. Additionally, HGH works to keep you healthy by promoting weight loss and muscle gain naturally.

Human growth hormone increases strength, promotes healthy weight gain, promotes fat loss, and slows down the aging process. The side effects of using HGH as an anti-ageing drug are minimal and rare. The anti aging HGH dosage is very low.

Human Growth Hormone Side Effects - the part we really need to know...

As growth hormone is naturally produced in the human body, the side effects of HGH treatment are rare. Generally, these side effects are caused by taking higher-than-recommended doses of HGH over longer-than-recommended periods of time. However, HGH has been known to occasionally cause:

Hypoglycemia is the opposite of diabetes. In people with diabetes, their bodies do not produce an adequate amount of insulin, leading to dangerously high glucose levels. People with hypoglycemia have too much insulin, leading to too low glucose levels. Because HGH increases the level of insulin in your body, some people have suffered from hypoglycemia after taking HGH drugs.

Acromeglia is a disease that causes abnormal bone growth. HGH cannot cause acromeglia, but it can speed up the progression of the disease in people predisposed to it.

Extended Belly
When used as a bodybuilding drug, HGH can cause a bodybuilder to have an extended belly if the drug is not used as directed. However, this defect is rare in users who take the drug as directed.

Carpal Tunnel Syndrome
Carpal tunnel syndrome is caused by a pinched nerve in the wrist. It can lead to loss of hand movement. HGH has been known to cause carpal tunnel syndrome in users who do not take the drug as directed.

Joint Pain
Because of its ability to cause growth in a person’s body, some users report joint pain while taking HGH. This side effect is usually temporary.


While HGH for the most part is well tolerated, there are some side effects that can occur. The biggest and most common side effect is bloating and joint pain. The chances of getting these can be minimized or even eliminated by utilizing the ramp up method discussed above.

If you are younger than your late 20’s, it would be very wise to enter an HGH cycle under the guidance of an MD, who can monitor and confirm whether your growth plates have fused. While abnormal bone growth with HGH use is not common, if used at the wrong point in your body’s development, it could cause disproportionate growth.

If you have a history of cancer or other tumors (at any age), it would be wise to get a complete checkup and be monitored by an MD to make sure that there are no active tumors before your HGH cycle. While HGH (and IGF-1) won’t cause cancer or tumors, they can create an environment that can allow already existing, active tumors to grow at an accelerated rate.

Beyond this, there really isn't anything specific that you would HAVE to take with HGH. There are supplements that you could take for specific conditions that are possible with HGH use. The way people react to HGH is a pretty individual thing. Some people get very little suppression of any kind, others don't see any gains from adding HGH because of significant enough suppression of one kind or another. Here's a general rundown of a few of the bigger ones.

For the slight thyroid suppression that is possible:
conservative - take nothing
moderate - t-100x, bladderwrack, coleus forskolin, selinium, zinc, chromium, copper
aggressive - T3 at a dose of 12.5 - 25 mcgs per day

For the insulin resistance that is possible:
conservative - 300mg of Alpha Lipoic Acid and 200 - 300mcgs of Chromium Piccinolate
moderate - 15mg of Actos - a prescription med to increase insulin sensitivity, Glucophage or Metformin to dispose of excess glucose and increase uptake in muscles.
aggressive - add a few IU's of insulin to your HGH cycle

For healthy test levels to best utilize HGH
conservative - do nothing
moderate - use Tongkat or Tribulus
aggressive - add 200-300 milligrams (or more) of testosterone weekly to your HGH cycle

For protection against prostate growth
conservative - do nothing
moderate - use Saw Palmetto (approx 2000mg)
aggressive - use Proscar or equivalent

For those that have a problem with breast tissue growth while on HGH
For those that suffer from this, there is a difference of opinion as to the cause. In the presence of adequate estrogen, HGH can prompt growth or breast tissue. Others theorize that HGH can raise prolactin levels, which can prompt breast growth.
The current consensus seems to be that the best approach for those with this problem is twofold - Take 200mg of B6 (or Bromo if B6 is not sufficient) and also use 20-40mg of Tamoxifen (Nolva) to control this. This is a pretty rare condition, but I have talked with more than a few bros that have reported problems of late.

Once again, I wouldn't say that all of these are necessary for everyone. I would use these supplements as needed to correct whatever conditions that arise with your HGH use. As stated above, reaction to HGH (and just about anything else we use) is very individual.

  • This information is provided by a global expert on the use and therapy regarding rhGH (somatropin) in a medical clinic setting in Puerto Vallarta, Mexico. That clinical experience of over 21 years with HGH is well documented and referred to by World-Class Athletics recuperating from injury and other European & North American Longevity Clinics and health facilities. That clincal facility were the first licensed medical suppliers of rhGH in a clinical setting within Latin America in 1993.

** Hypopituitarism Diagnostic Tests

AK80's picture

I would like to get some opinions on whether or not taking 5 iu before bed every other day would be effective enough? I have 200 iu on hand ready to be reconstituted. This will give me 80 days worth unless I do it every day, then 40 days worth. Thank you!

Pmob's picture

I know someone wrote a good thread about this years ago. Dig around

In a promo × 1
lifting211's picture

I'm a bit confused about the insulin syringes. You say u-100 insulin syringe. When I look to purchase those there is a variety of U-100 syringes.

What g should it be?

How many mls?

What is the difference between a standard syringe and a insulin syringe?

When the hgh is not combined and is still in powder form does it still have to be refrigerated?

I am still very confused about dosing and bac water needed. Will keep researching but thanks for this thread I will keep rereading it as well. To fully comprehend the great info.

Feeha003's picture

30g 1/2" works well

1ml/cc works

Insulin syringes are insulin syringes. You can't find "standard syringes" that small.

Always refrigerate

Bacteriostatic water

Still confused? Don't attempt any of this.