posted Thu, 05/21/2026 - 10:29
332
+ 2 Mots-C & SS-31
ad
Is anyone taking these together? I've been researching the two and they apparently have different uses. Which do you take first, what's your dosage and frequency?
Bonus points if you want to explain your sides.
TIA!
- Bookmark
- 2
- 0
What site is best for ss-31 and Mots-c?
Can’t discuss sources on forums but just take some time and look through recent reviews or source discussion pages
Drift.ModeI have ran both together, and separated. I was not impressed with SS-31 and do not plan on purchasing ever again. Mots - c on the other hand is like god mode, & have a kit en route right now.
Did you have sides with ss-31 or just no noticable gains/effects?
Drift.ModeAt 5mg Daily there were no sides, but did not notice anything either. The doses on the pharmaceutical trials it’s 40mg daily, so maybe that the problem
Gainz411From what I’ve researched and from my own experience taking both, they actually seem to complement each other pretty well rather than overlap. SS-31 seems more focused on repairing/protecting damaged mitochondria, while MOTS-C is more about improving metabolic signaling and making the mitochondria work more efficiently.
Personally, I run SS-31 first for 4 weeks, then MOTS-C for 8 weeks afterward. Basically back to back. To me it makes more sense to fix/support the mitochondria first before trying to push performance and metabolic output from them.
That said, if you’re a younger guy with healthy mitochondria already, you probably don’t even need SS-31 and could likely just use MOTS-C alone.
Also check out the forum “Exploring Peptides” if you haven’t already. It’s peptide-focused and honestly one of the more informative places I’ve found for this stuff.
I had no side effects. My wife had horrible pip and gave up on mot after 2 weeks. I’ve taken mot cycles several times. Doing cycles of 15mg a week and 30mg a week.
Thank you! Checking out exploring peptides now. I'm 41 so thinking ss-31 would be beneficial. Do you see noticeable energy level increase with Mots-c?
What dosages are you running each protocol?
Gainz411I think it’s subjective for each person. Because we all have different starting levels. But for myself Ss-31 5mg daily. Mot-C 5mg 3 times a week for 6 weeks then last 2 weeks 5mg twice a week.
My last cycle I did 30mg a week. 3 times a week. I’m doing a cut now and decided not to include it in this time.
I agree and the research agrees as well atleast what I’ve read but having someone with personal experience with the exact same protocol definitely helps me with my decision that’s exactly how I’m gonna run it. Thanks dude
I have a kit of each that I’ve been planning on running. I keep doing research that pulls me all different ways.
So far from what I can see it seems like the best way to go about it is to run ss-31 first to repair the mitochondria, which intern would make MOTS – C more effective.
I think the dose I’m gonna run for the SS – 31 it’s gonna be 5 mg a day studies. I’ve seen have guys doing doses of like 40 mg a day, but I ain’t got time or money for that shit.
I’m still up in the air on how I’d run the MOTS – C probably 5mg eod
Research has been conflicting for me too. Trying to get a comfortable baseline starting dose and work off of that. I like the idea of running ss-31 first.
Yeah that’s definitely the best protocol I’ve seen. I was gonna skip ss-31 originally but I’ve had so much oxidative stress I figure it can’t hurt to clean the pipes