• up
    • 4
    • down
    • 0
    • 4
  • BESTGEAR.WS's picture
  • SRC
  • 34
  • Peptides Brief FAQ

  • BESTGEAR.WS   •   Thu, Nov 7th, '19 18:03   •   1 reply, 59 views

Small peptides brief FAQ, i hope will be helpful for some one. It is translated from other language, so sorry if something will be not correct on 100%.

Releasing Growth Hormone Peptides:

GHRP-6 - Growth hormone releasing peptide -6 releasing growth hormone peptide. Ghrelin mimetic. Stimulates the secretion of growth hormone. In addition, it blocks somatostatin and stimulates the release of ACTH and prolactin. It provokes a terrible appetite after injection. May interfere with sleep. Subject to the effects of carbohydrates and free fatty acids after application of the peptide. In undissolved form, it is best to store in a freezer. Diluted with water for injection. The solution is stored only in the refrigerator for about several months without loss of useful qualities. The optimal dosage is 1 μg per 1 kg of body weight. The maximum dosage is 3 mcg per 1 kg of body weight.

GHRP-2 - Growth hormone releasing peptide -2 releasing growth hormone peptide. Ghrelin mimetic. Stimulates the secretion of growth hormone. In addition, it blocks somatostatin and stimulates the release of ACTH and prolactin. It provokes the occurrence of moderate appetite after injection. May interfere with sleep. Subject to the effects of carbohydrates and free fatty acids after application of the peptide. In undissolved form, it is best to store in a freezer. Diluted with water for injection. The solution is stored only in the refrigerator for about several months without loss of useful qualities. The optimal dosage is 1 μg per 1 kg of body weight. The maximum dosage is 3 mcg per 1 kg of body weight.

Hexarelin - releasing growth hormone peptide. Ghrelin mimetic. Among all ghrelin mimetics, it stimulates the secretion of growth hormone at the highest level. In addition, it blocks somatostatin and, among all ghrelin mimetics, it stimulates ACTH and prolactin at the highest level. Does not provoke appetite after injection. Disturbing sleep. Least affected by carbohydrates and free fatty acids. For 1 month of administration, it provokes a desensitization of the receptors of the somatotropic pituitary cell. In undissolved form, it is best to store in a freezer. Diluted with water for injection. The solution is stored only in the refrigerator for about several months without loss of useful qualities. The optimal dosage is 1 μg per 1 kg of body weight. The maximum dosage is 3 mcg per 1 kg of body weight.

Ipamorelin - a releasing growth hormone peptide. Ghrelin mimetic. Stimulates the secretion of growth hormone. In addition, it blocks somatostatin and has no effect on the stimulation of ACTH and prolactin. It does not cause appetite after injection. Helps normalize sleep. Exposed to carbohydrates and free fatty acids. In undissolved form, it is best to store in a freezer. Diluted with water for injection. The solution is stored only in the refrigerator for about a month without loss of useful qualities. The optimal dosage is 1 μg per 1 kg of body weight. The maximum dosage is 3 mcg per 1 kg of body weight.

Somatoliberin analogues (affect the somatotropic pituitary cell via the GHRH-R receptor):

GHRH - Growth hormone releasing hormone - releasing the hormone of growth hormone, aka Somatoliberin, aka GRF 1-44. The half-life in blood is about 5 minutes. Stimulates the secretion of growth hormone. It is blocked by somatostatin. Exposed to carbohydrates and free fatty acids. In undissolved form, it is best to store in a freezer. Diluted with water for injection. The solution is stored only in the refrigerator for about a week without loss of useful qualities. The optimal dosage is 1 μg per 1 kg of body weight.

GRF 1-29 - An analog of somatoliberin. He is Sermorelin. The half-life in blood is about 5 minutes. Stimulates the secretion of growth hormone. It is blocked by somatostatin. Exposed to carbohydrates and free fatty acids. In undissolved form, it is best to store in a freezer. Diluted with water for injection. The solution is stored only in the refrigerator for about a week without loss of useful qualities. The optimal dosage is 1 μg per 1 kg of body weight.

D-Ala2 GRF (1-29) - An analog of somatoliberin. The half-life in blood is about 10 minutes. Stimulates the secretion of growth hormone. It is blocked by somatostatin. Exposed to carbohydrates and free fatty acids. Diluted with water for injection. The solution is stored only in the refrigerator for several weeks without loss of useful qualities. The optimal dosage is 1 μg per 1 kg of body weight.

Mod GRF 1-29 - An analog of somatoliberin. He is CJC 1295 (without DAC). The half-life in blood is about 30 minutes. Stimulates the secretion of growth hormone. It is blocked by somatostatin. Exposed to carbohydrates and free fatty acids. In undissolved form, it is best to store in a freezer. Diluted with water for injection. The solution is stored only in the refrigerator for about a month without loss of useful qualities. The optimal dosage is 1 μg per 1 kg of body weight.

Tesamorelin - Tesamorelin. Somatoliberin analog. He is Egrifta. The time of complete dissolution in the blood is about 8 hours. Stimulates the secretion of growth hormone. Not affected by somatostatin. Not affected by carbohydrates and free fatty acids. In undissolved form, it is best to store in a freezer. Diluted with water for injection. The solution is stored only in the refrigerator for about a week without loss of useful qualities. The optimal dosage is 1 mg per day.

CJC 1295 - An analogue of somatoliberin. He is CJC 1295 with DAC. The time of complete dissolution in the blood is about 28 days. Stimulates the secretion of growth hormone. Not affected by somatostatin. Not affected by carbohydrates and free fatty acids. In undissolved form, it is best to store in a freezer. Diluted with water for injection. The solution is stored only in the refrigerator for about a week without loss of useful qualities. The optimal dosage has not been established.

Analogs of the mechanical growth factor:

MGF - Mechano Growth Factor. Mechanical growth factor, aka IGF-1ec. Stimulates hyperplasia by dividing myosatellite cells (satellite cells of skeletal muscle). The half-life of several minutes. Intramuscular injection into the "lagging muscle". In undissolved form, it is best to store in a freezer. It is diluted with water for injection, and sodium chloride can also be used as a solvent. The solution is stored only in the refrigerator for about a week without loss of useful qualities. The optimal dosage has not been established. It is able to suppress the mineralization and differentiation of osteoblasts.

Peg MGF - Pegylated Mechano Growth Factor. Pegylated mechanical growth factor. Stimulates hyperplasia by dividing myosatellite cells (satellite cells of skeletal muscle). The half-life of several days. Injection subcutaneously or intramuscularly. In undissolved form, it is best to store in a freezer. It is diluted with water for injection, and sodium chloride can also be used as a solvent. The solution is stored only in the refrigerator for about a week without loss of useful qualities. The optimal dosage has not been established. It is able to suppress the mineralization and differentiation of osteoblasts.

Recombinant Insulin-like Growth Factor:

IGF-1 - Insulin-like growth factor-1. Insulin-like growth factor 1. In the body, it is produced by hepatocytes of the liver in response to stimulation by growth hormone. In an unbound state, the half-life is less than 10 minutes. In an unbound state, it can cause the growth and development of muscles, cartilage, bones, etc. It binds to specific binding proteins (IGFBP-1, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, IGFBP-6, IGFBP-7), due to which the half-life is prolonged, one or another IGF-quality is stimulated or suppressed one. Excess IGF-1 inhibits the natural secretion of GR. IGF-1 is able to stimulate the growth of cancerous tumors. IGF-1 does not lead to diabetes. IGF-1 does not directly affect the lipolysis process, since adipocytes (fat cells) do not have “native” IGF-1 receptors. It is best dissolved at home with a solution of 0.9% sodium chloride ("saline" solution). After dissolution, the degradation period can be about 7 days. The optimal dosage has not been established. Injections can be done either subcutaneously or intramuscularly.

Long R3IGF-1 aka IGF-1 LR3 - Insulin-like growth factor 1 in which Arginine is replaced by Glutamic acid in the 3rd position and a chain of 13 amino acid residues is added. The main difference from IGF-1 is that LR3 is much less able to bind to binding proteins and act on the IGF-1R receptor on its own. The half-life after injection is 20-30 hours. It is best dissolved at home with a solution of 0.9% sodium chloride ("saline" solution). After dissolution, the degradation period can be about 7 days. The optimal dosage has not been established. Injections can be done either subcutaneously or intramuscularly. "Effective" and side effects are the same as those of recombinant IGF-1.

DES (1-3) IGF-1 - An insulin-like growth factor 1 in which the last 3 amino acid residues are removed from the amino acid chain, making this hormone more “more powerful” in terms of its activity (both positive and negative). The half-life has not changed; it is also 10 minutes as with IGF-1. It binds to specific binding proteins (IGFBP-1, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, IGFBP-6, IGFBP-7), due to which the half-life is prolonged, one or another DES quality is stimulated or suppressed ( 1-3) IGF-1. It is best dissolved at home with a solution of 0.9% sodium chloride ("saline" solution). After dissolution, the degradation period can be about 7 days. The optimal dosage has not been established. Injections can be done either subcutaneously or intramuscularly. "Effective" and side effects are the same as those of recombinant IGF-1.

Thymosin Beta 4 - Thymosin beta 4. Protein, abundantly present in many tissues and body fluids. The main function is the binding of G-actin. It may be useful to improve tissue repair, maintain flexibility, strengthen the walls of blood vessels, restore the epicardium. May provoke the migration of cancer cells. In undissolved form, it is best to store in a freezer. It is diluted with water for injection or "saline" sodium chloride. The solution is stored only in the refrigerator for about several weeks without loss of useful qualities. The optimal dosage is 200-500 mcg.

Gonadorelin - Gonadotropin releasing hormone. It stimulates the abundant production of FSH and LH, as a result of which, during use, testosterone production and spermatogenesis increase. With short-term use leads to a violation of the production of testosterone, FSH and LH. Prolonged use leads to chemical castration. In undissolved form, it is best to store in a freezer. It is diluted with water for injection or "saline" sodium chloride. The solution is stored only in the refrigerator for about a month without loss of useful qualities. The optimal dosage has not been established.

HGH Frag 176-191 - A fragment of human growth hormone from the 176th to the 191st amino acid residues. Responsible for lipolysis. Blocked by insulin. Very prone to degradation. In undissolved form, store only in the freezer. It is diluted with water for injection or "saline" sodium chloride. The solution is stored only in the refrigerator for about one week without loss of useful qualities. The optimal dosage is 200-500-1000 mcg.

DSIP - Delta sleep-inducing peptide. The peptide theoretically increases the length of the long sleep phase, thereby improving sleep and theoretically indirectly is able to increase the secretion of GH.

Melanotan II (MT2) - Melanotan 2. A synthetic analogue of Alpha - melanocyte-stimulating hormone. Melanotan 2 stimulates the growth of skin melanocytes and enhances the production of black pigment melanocytes - melanin, which enhances skin pigmentation and increases skin resistance to ultraviolet radiation. It has the ability to bind to MC1R, MC3R, MC4R and MC5R receptors. The MC1R receptor is responsible for skin pigmentation; MC3R - is involved in the regulation of blood pressure; MC4R - is involved in the regulation of nutrition; MC5R - is involved in the exocrine function of the pituitary gland. MT2 is able to reduce appetite and increase libido. A theoretically effective dosage depends on the skin phototype and body weight, but from a practical point of view it is better not to bother with these calculations. Everything is much simpler. It is better to start with 250 mcg per day and increase the dosage of 250 mcg every day until the dosage reaches 1 mg, and this 1 mg needs to be punctured for several more days. If this "therapy" will be carried out during sunbathing in the sun or in the solarium, then a person can independently "regulate" the level of tanning and the level of dosages. Those. with intensive “sunbathing” for a good tan, sometimes 1-2 weeks of using MT2 is quite enough. Side effects of MT2 include loss of appetite, involuntary erection, impaired pressure, nausea, the appearance of small moles throughout the body, temporary darkening of the hairline (throughout the body). To prepare the solution, both water for injection and saline can be used. When diluted, it is stored in the refrigerator for about 6 months without loss of useful qualities.

PT-141 (Bremelanotide) - Bremelanotide. The synthetic analogue of Alpha is the melanocyte-stimulating hormone. This is a metabolite of Melanotan II, which has the ability to activate MC1R, MC3R and MC4R receptors. RT-141 is able to increase libido, but this drug does not work for everyone. Side effects include increased pressure. The optimal dosage has not been established, although some sources indicate dosages of 0.5-2 mg. The practice of use at any dosage shows that the only “sexually positive" effect that can be expected after the use of RT-141 is an erection, and this is not always the case. The use of this peptide did not cause any special effects in women.

Comments

  • Tron's picture
  • EXP
  • 700
 
  • Tron
  • 3 days ago

+2 for taking the time to do this.