Exemestane's half life in the male body is actually
very short (~9 hours) and it is quickly eliminated,
however, since as soon as it enters your
bloodstream it quickly destroys 80-90% of the
aromatase enzymes present in your body, it is
effective in maintaining significant reductions in
estrogen for up to 72 hours after a single 25mg
dose. Estrogen levels only begin to rise again after
your body has begun to make new aromatase
enzymes to replace the ones destro by
exemestane.

There is a great study on the pharmacokinetics of
exemestane in men which found the following:
-24 hours after one 25mg dose estrogen levels are
reduced by 70-80%
-72 hours later estrogen levels are still 40% below
baseline even though the drug itself is almost
completely eliminated
-120 hours after initial dose estrogen levels return
to baseline (without rebounding)

this means that you can find the timing and dosage
that works for you, i've seen some guys
recommend between 25mg ed and 12.5mg e4d,
and you can see why both are effective while
providing different levels of estrogen suppression,
and it is this flexibility that makes exemestane such
a versatile anti-e.

dude your a troll and a half,i see you everywhere posting bullshit. the half life is 24-27 hours, look it up before you start correcting people with innacurate information

Maybe you should check the date of the post before you post usless shit . This is from 7 months ago. This guy is a lot more knowledgable now then he was back then. SMH. And for the record you are correct the half life is very short, but many many people dose exemenstane eod. It works.

And 12.5mgs ed would crash anyone's estrogen. 6.25ed had me around 35 which is normal range . Imagine what 25ed would do. Atleast to me.