posted Wed, 06/13/2012 - 17:10
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+ 1 CJC 1295 Dac and Ipamorelin dosing issues women
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Ok, so the wife wants to get into peptides to accelerate her fat loss. Her diet and training regimen is good.
Was thinking CJC 1295 DAC twice a week and Ipamorelin every night before bed since that is what I've read so far. What about actual dosages? The number I keep seeing tossed around is 1mcg/kg. However, that seems to be the dose for CJC1295 without DAC.
Any female that has used this stuff extensively care to chime in as far as dosages and rate of injections?
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Dosing is not female or male specific when dealing with peptides. Rule of thumb is 1mcg/kg of body weight. Typically 100mcgs is considered the saturation does but you can go higher but the results increase only slightly and tend to get more expensive for such a small increase in results. Also I would suggest using ModGRF 1-29 instead of the CJC1295 w/DAC and CJC w/o DAC. CJC1295 with DAC cause a small GH bleed which you don't want. As for CJC1295 w/o DAC removing the DAC you would still have a dangling Lysine amino acid at the end which is not present with ModGRF 1-29. CJC1295 w/o DAC has 30 amino acids which makes it unstable due to the dangling Lysine which is used to attach the DAC.
Just my thoughts from what I have researched.
dragonsfly033Hey, I am just trying to figure out when and where this urban legend of cjc-1295 with dac causing hgh-bleed was born. I have read all the scientific studies carried out and I have never found an evidence of hgh bleed. Could you please tell me where did you find it ? thanks
http://endo.endojournals.org/content/146/7/3052.full
I also would like to see the scientific studies that you have read on this as there is a lot of informaton out there and most of it broscience but I have found this to be the most realistic study that has been done besides ones personal experience.
dragonsfly033hi bro, firstly the study was partially carried out in vitro not in vivo. It means they worked on celIs not living organisms. It is an experiment without scientific relevant for human beings. I have read the abstract but I was not able to find any scientific evidence of gh-bleed. Unlike gh-bleed I found a statement that reported:
" After 2 h of exposure to CJC-1295, the level of GH eventually returns to the baseline value although the immunoreactive GRF level remains elevated. The lowering of GH concentration can be attributed to a number of reasons, such as down-regulation of the GRF receptor (22), a drop in pituitary GH content (28), or the multicomponent feedback loop regulated by somatostatin (29) and IGF-1/insulin (30). At this point, no further experiments were undertaken to explain the reduction in plasma GH, because it is well established that there is receptor desensitization to GRF observed in rat cells, and the physiological relevance has not been correlated to receptor down-regulation in humans (31)......NO GH BLEED ON THE CONTRARY GH REDUCTION AFTER CJC-1295 ADMINISTRATION..... It has also been clearly established that GH secretion is pulsatile in the presence of sustained plasma concentrations of GRF (6, 32, 33). The pulsatile response to the administration of CJC-1295 will need to be demonstrated in a more appropriate model (34). This subject will be addressed in a subsequent paper in this series. In summary, in vivo bioconjugation of maleimido hGRF1–29 derivatives to serum albumin occurs after a single bolus sc administration and is a useful tool to increase the plasma residence time of these particular bioactive peptides. The results reported herein demonstrate that a hGRF-albumin conjugate is able to interact with, and activate, the rat GRF receptor on the anterior pituitary to produce a high level of GH in plasma over time, leading to the discovery of CJC-1295 as a long-lasting hGRF analog."
So where and when was gh-bleed legend born ? I will be asking for an answer.
If you want to read the few studies pubblished on cjc-1295 with dac go here:
http://www.ncbi.nlm.nih.gov/pubmed/?term=cjc-1295
dragonsfly033hi bro, I have recently posted my results on cjc-1295 with dac http://www.eroids.com/pics/lab-test-after-4-month-on-cjc-1295-with-dac-f... I am a male but my female mate has been using it for months with good results. So what I can tell you based on my experience on my female mate is this: 5mg winstrol tabs or oxandolone a day+ cjc-1295 with dac 2mg a week (1 vial a week) + 500 mcg hgh frag 176-191 a day is a good stack to speed up fat loss. You have to use both aas and peptides to see results and it takes al least 4 months. This is quite a fair dosage without virilization side effects. Winstrol or Oxandrolone will help her to gain muscle mass to accelerate metabolism, cjc-1295 with dac will raise her hgh production for fat loss and igf-1 production, hgh frag 176-191 will let her burn fat at a faster rate. This combo worked amazingly for my female mate. Hope that will help.
Brother I'm not a female and never used that product you were discussing but I'm in the tail end of a serious fat loss process. 90 days in and I have 30 days left. Down 40 pounds to date. Going to go another 5 or 10. With me it was all diet. I mean I lift 5 days a week and take aas but the lifting and the chemicals are what's keeping from looking like a crack head. The diet is dropping the fat. Check out the diet I designed for myself. I posted it in the weight loss section. I've told this to a only a few people. I have done zero cardio in the 3 months.
p.s. good luck on your karma thing.