Since its 200 mcg per ml that's 20 mcg per number on a 1 ml insulin pin. I pulled the needle out and she uses it like an oral dropper. She started with 20mcg per day and worked her way up to 40 mcg. She goes 2 weeks on 2 weeks off. She weighs between 115 and 120. Not sure because she won't get on the scale. I did 40 mcg the one time I tried it and weighed 225 at the time. Start off low and work your way up. It's a bad feeling to be on too much clen. Real bad.