All anabolic steroids have a negative effect on cholesterol. They all lower hdl(good) and raise ldl(bad) levels. According to Dr. Meir Stampfer of Harvard Medical School, each 1-point drop in HDL represents a 6% increase in the risk of heart disease. That’s assuming total cholesterol remains the same, but as we know in fact that it rises on gear so the risk is much greater. Based on that you can count on a minimum 240% increase in the likelihood of developing heart disease, while on gear.
What does this mean long term? Many people say that you don’t need to worry, and that after a cycle your cholesterol levels will return to normal, but arthrosclerosis develops over time as plaque builds up in your arteries. You can be fine one month and the next month have a heart attack from 90% blockage.
Another point of fact is a study that shows when 39 subjects were injected with 500 milligrams of testosterone ethanate, after only 2 days total cholesterol was up by 15%. So the changes happen extremely quickly.
And since we all know that estrogen protection is necessary for most of us on cycle, it is also important to note that all aromatase inhibitors when taken in conjunction with aromatizable steroids, the effects on suppression of hdl(good cholesterol) will be significantly more pronounced. Another important thing to note is that while aromatase inhibitors do have a negative effect on hdl, an alternative to using an ai, would be using nolvadex(tamoxifen) which does not display the same anti-estrogenic (negative) effect on cholesterol levels.
So after all of this information, we still decide we want to juice, what can we do to try to keep our cholesterol in check? Here is a list of products that we can use for general cholesterol health. From my research I have listed these in order of effectiveness.
Niacin- a general dose for cholesterol health is between 1000-1500 mgs a day
Fish oils- 4000-6000 mg a day
Red yeast rice- 1200-2400 mg a day. Red yeast rice is basically fermented rice that shares the same active ingredients as the main stream prescription cholesterol lowering statins on the market. It is known to have a decent effect on cholesterol maintenance. However it is important to note that is is only beneficial for short periods of time such as 3-4 weeks before cycle and then continued through pct. It is also good to note that this product is known to lower concentrations of coq10 in the heart and liver so either a pre made supplement including this or additional supplementation of coq10 at 300 mg per day will be needed.
Allicin- an extract found in garlic which is shown to lower blood pressure and lipid levels. It has established reports of its ability to fight cancer. Purer forms of this extract are the best to use.
Policosanol-Dosage of 10-20 mg a day, is made up of a blend of fatty alcohols known to be beneficial towards cholesterol maintenance. This supplement sometimes takes up to 3 months before full benefits start to show themselves and is recommended to be stacked with fish oils, which create a synergetic effect.
Fenugreek- is known to help during pct for hpta recovery but also shows some slight benefits towards lipid health.

have a look into taking niacin after your cycle mate...

Or

If you stay on big doses year round
(like some idiot called poofinger), Pay an endo to do blood work at 6 week intervals, stay away from winny, and look into getting prescribed a statin (cholesterol) and an ACE inhibitor (BP)...
A good endo will be able to keep you in normalish ranges no probs.