SARMS: MK-2688 (Ostarine) Negative Feedback?
ive had an increasing interest in sarms and their anabolic effect on the body. mk-2866 otherwise known as ostarine seems like a great product especially when coming off cycle, but what i am really interested in is negative effects reported from studies, and its been a little difficult for me to come by. anyone who can post a link or share some data they have found that has reported some negative feedback would be great.
personally i am looking at something to maintain lean mass when off while burning fat, and this product sounds helpful. i was also interested in gw-501516, which has been reported to help melt off fat, has certain studies backing it claiming the compound gave rats cancer. with a little cancer history in my family and although these reports are conflicting on the basis they used 100 - 300 times the dosage on rats that developed cancer i still dont feel comfortable using it.
now you can get an idea of what ive had trouble finding for this compound.
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thanks for the feedback. i think this stats thing is a little overrated, but you asked so shall you receive. im roughly 30, have done my fare share of cycling that i dont recall what number im on. roughly 212 lbs, 5'11. bf% is about 17%. im experienced with test e, c, p, deca, npp, var, tren a, mast p, eq, letro, nolva, toremifine citrate, clomid. peps ive used ipam, grf1-29, igf-lr3, & gnrh. clen as well. lift 5 times a week, cardio roughly 6 times a week, half hour post workout, hour on non lifitng days.
i would use peptides again but havent been able to research much more than the stuff ive used, and those were a bit disappointing. plus i dont have the funds to support a 4-6 month pep supply, which seems to be the common consideration when using them.
meals i get 6 a day, and am currently carb cycling.
let me know if i didnt address the stats question completely.
and dont let the small 36 karma confuse you, i completely understand the research aspect. my main concern right now is making sure that ostarine doesnt have any sort of reporting of tumor causing, heart disease enabling, long term suppression properties to it.
I researched ostarine for ages before I tried. No tumor cases, no cholesterol, hart issues no liver toxicity. Only binds to receptors in skeletal muscle and ...bones I think. It's ok stuff but you need quite a bit of it! And some say it does slightly shut you downanyway while some say it does not. I guess best to take some not androgen related compound. Hgh igf etc.
Lgd4033 is better but it does shut u down and rises LDL.
thanks, much appreciated as your insight is helpful.
Why not look into peptides some more? They are great for helping maintain mass and you wont have to worry about shut down or suppresion on them
I agree with goliath90. I tried ostarine twice(1 month at 1 ml a day and later 6 weeks on 1.5 ml a day). It seemed like took well over2 weeks to notice it was working. Strength was holding after cycle for quite a bit. I got a little bit leaner too. But it can't compare to anabolics. It's good to use it when you taking time off . Don't expect much from it. But yes no sides at all.
I can't recommend anything until I know your stats, however I can share some more details related to your question.
The negative aspects of SARMs are similar to those of AAS, but on a much smaller scale. Being that SARMs are tissue selective, you see a lot less of things like suppression but you still need to be prepared and do labs, especially on your first cycle. A good example is LGD, it is several times more anabolic than Ostarine, however it is slightly less tissue selective and slightly more suppressive (dose dependent).
Read all of the studies on Ostarine, including the power trials. No tumor-genesis was reported, no spike in liver enzymes. Does that mean you should just go for it? No, be prepared for a full PCT, however I have never had more than very minor suppression on Ostarine alone.
glowinthedark makes a good point, be fully educated before putting your body through anything. As an alternative to Gw-501516, have a google at AICAR. Happy to make some suggestions once stats are posted.
Bro, need your stats - personal profile incomplete. We not supposed to begin any threads in this section of the site without that information.
@TimberDog
-10 for negging for asking for stats and not even leaving a comment to own it >: /
Just saw your post Hollywood. It was certainly nothing personal. I just thought the crux of the question was on the potential negative effects of ostarine and the stats not therefore pertinent to answering the question. In this case, I thought by withholding info (assuming Gearhead has some experience with it, which he often does) actually deprived the OP and me since I was interested in gaining some valuable insight into this compound. So no offense Gearhead and after having read the rules again, I can see where I was errant in downgrading your comment. My apologies.
AnonIt's been a little over a yr since I last tried Ostarine and can't remember any notable sides. It really seemed to lean me out really well, producing a lot of vascularity, but not much if any gains.
Ostarine's negative effect as far as suppressing natural levels? It shows suppression but it depends on the person and the dose taken. It seems like when taken with SERMs the suppression is not worth mentioning. If you run this compound do around 6 week runs and get bloodwork during it if you're concerned. I'm using Ostarine next PCT, yes DURING PCT, 20/20/10/10. I'll post my success on this forum when completed but many other boards are showing LBM increases during PCT while using this.
GH-501516 is too risky for me to try but others say it's perfectly fine. Any compound that has proven to give cancer at a high dose is just not something I'm willing to risk. Mice predisposed to polyps had an increased in polyps when using it. That effect seems to be negated with the use of Tribulus.