Muscle Freak's picture
Muscle Freak
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+ 1 Trouble losing weight on lithium and seraquel

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I have been desperately trying to lose weight before I start my next cycle. It has been about 2-3 years since I have run anything others than trt and I wanted all my ducks in a row. Mind you I’m not obese by any stretch of the imagination, but it would be nice to be able to see my abs again at a relaxed state. I am bipolar and take meds to keep me sane, but one of the side effects is weight gain. I have been able to lose 10 or so pounds, but now I am stuck and no matter the calories I consume or the cardio I endure, I just can’t seem to lose anything at all. If any of you have similar circumstances, any advice would be welcomed.

Johnny Bravo's picture

I was on lithium for years because of bipolar. It alters thyroid function and the doctor needs to check it regularly. I read u r having shakes and mine became worse as my dose went higher. It is a salt as well. After about 2 months of 1250mg a day I started getting horrible back pain. Eventually went to the hospital and once I arrived started throwing up red stuff and the doc asked about med changes. Told him about my lithium, ran bloodwork, then came back panicking and hit me with dilauded and Valium. Woke up the next day to be told I had kidney failure and my heart went from 140 bpm to <60 from lithium toxicity. I had a lesion on my kidney for months. All is well and healed now though. Be on high alert with lithium.

Seroquel made me a zombie especially at 1000mg a day. Got down to 50mg and eventually I’m off it now. I kept waking up in snickers wrappers and covered in peanut butter every morning cuz the night hunger. Apparently I would even sleepwalk to the pantry and even sometimes heat up food with no recollection. Being on and off that for years in combination with all the other meds I’ve been on has definitely added some unwanted midsection mass that’s very stubborn to lose. When I was on zyprexa I gained 13 lbs in the first week. The last time I gained 51 lbs in 5 months.

With Latuda be careful with restless legs syndrome. It’s not as bad as with abilify or how some people get it with seroquel but I’m sensitive to it and I was banging my knees into walls for relief. It’s from an imbalance between cogentin and dopamine and asking to be prescribed cogenin will help but it will give u blurry vision to the point you need glasses.

Personally I found depakote to work for me I just need my serum levels checked like lithium and my liver values tested since it Can impact the liver like lithium does to the kidneys and thyroid. Fee free to pm me any questions I’ve been on everything except the “schizo shot” until I finally stabilized. It’s hard to train and eat right when ur mind isn’t in the right place so I think that should come first before dropping meds but that’s just my experience. Gaining self esteem thru esteemable acts really made a difference and thru some hard work in and out of the gym I went from stomach ulcers from 14 psych pills a day down to two prescriptions. It’s a long road with sacrifice but worth it

Muscle Freak's picture

I get my lithium levels checked pretty regularly and the dr said I’m at the limit of my dosing. As for depokote I have to steer clear of that stuff. It really fucks me up and I can’t function. I was wrong before it’s actually lamicil and I seem to be tolerating it pretty well. Thanks for all the good info +1

Johnny Bravo's picture

I was told based on genetics lithium seraquel lamictal combo would work best for me since it does for a close relative. Too bad it turns out I’m allergic to the lamictal. For whatever reason my body acclimates to dose over time. Like 250mg will give me a blood level of .5 then months later I need 500mg then 750 etc. etc. to achieve the same blood level. Then eventually the side effects outweigh the reward and I have to switch. I was tolerating high lithium for a while but in between my regular 6 month blood tests my kidneys went on hiatus.

Muscle Freak's picture

There you go, evened you out man. What you said didn’t deserve that imo

Manshit's picture

Not only that but quite a few members are recovering addicts.The regiments of lifting help them with recovery.These drugs are prescribed for recovery as well.

Muscle Freak's picture

I agree. I was surprised to learn so much. Already got meds changed so fingers crossed

Muscle Freak's picture

I don’t have much problems keeping the cravings at bay. My problem is that even though I am eating clean, I still keep the weight on. I haven’t gained any more, but it’s playing hell trying to lose. I’ve lost about 10 lbs and now there is nothing I can do.

november1's picture

Sorry to hear about your problem man.
Sadly I must admit I Am diagnosed Bipolar as well. It is very hard to work and live healthy life with this becouse you never know when you can snap. I don't use meds anymore, I refused, I got lethargic and slow, plus fat stores. I could make rationale decisions when in them and my reflexes was down. I was becoming potato. And the problem was meds - saraquel.

Hope you find a way to deal with this.
I didn't, but I'm better if it anyways.

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Muscle Freak's picture

I have thought about stopping the meds many times. My wife tells me absolutely not when I talk about it tho. Mentally I’m much better on my medicines, but the sides are killing me. My doctor changed my meds today so hopefully things get better soon. Seroquel is being tapered off so things should get better soon. Hang in there bro

Muscle Freak's picture

I’m actually waiting to see my psychologist right now; as ironic as that is. I’m going to tell him my plans. I hope everything goes well.

Muscle Freak's picture

I have noticed a lot of these symptoms. With the diet and exercise program I’m on now I would be shredded. I really don’t enjoy taking it, that and I shake like I have Parkinson’s from the high dose lithium. +1 Thanks for the info

Muscle Freak's picture

My movements are really jerky when I go to grab something. I’m already type 1 diabetic so nothing to worry about there. I just had a long chat with my doc and got him to change my medicine. He put me on latuda. Ever heard of it. He was hesitant to ok aas usage, but I told him the mild compounds I would be on and he conceded. The only drawback is I have to see him every week when I start.

Manshit's picture

See my first response about Latuda.Weight gain is one of the package warnings.Be very careful!

Muscle Freak's picture

I saw your response and read the packaging thoroughly. The only weight changing side effect that I could find was that I made you lose weight. Don’t think I won’t remember what you said however. He said there were other medications I could try.

Muscle Freak's picture

It’s kinda a trial kinda things. I can get off whenever. Thatbwhen the insurance start paying the big bucks. I read the drugbinfo pamphlet and all I found is weight loss. I’m ccrossinf my fingers here lol

Manshit's picture

Lithium is a stabilizing drug and shouldn’t be the problem,though it may cause you to tremble.Seraquel is known to affect appetite and even nutrient use.It can make you skinny or fat depending on your personal make up.It may not be either.Talk to your Dr and ask him his opinion.I had a female client that was prescribed Letuda,she gained sixty pounds before her Dr decided to go another route.Weight gain was right there in the adverse reactions of the packaging.In other words have a very detailed discussion with your Dr.

Manshit's picture

I agree.I had a bout with depression after college football ended.Lucky for me I had a very good dr.He ran a battery of test and found my testosterone was in the dumps.Corrected that and my depression went away.

Sam I Am's picture

I can relate. I'm on remeron and within 45 min of takeing it I'm in the fridge...

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Muscle Freak's picture

Preach brother

Muscle Freak's picture

I think it’s the lithium that causes me problems. My dr. Now would not be the one to ask. It hasn’t bothered me in the past, but you are right and I need to look into it more.

stairmaster's picture

I'm not sure if steroids are good for you. Steroids can increase psychical problems there are even a lot guys they get crazy on roids without any pre-existing conditions.

I don't know how lithium works but I know a guy who takes seroquel and he's very skinny cause he has no appetite.

I would ask a good doc if your plan could be a problem for your bipolar disorder! Try to find a doc which is experienced and has much knowledge at psychatric drugs and steroids.

Muscle Freak's picture

Thanks for the concern. I took your advice +1