Sciroxx's picture
Sciroxx
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+ 4 GH effects, and what is the optimal length of usage ?

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I've been asked many times by members how really GH effects the body ? Many also are interested to know for how long it's effective to use GH ? if one has a limited budget is good to use for several weeks ?

The GH-IGF1 is possible the most complex hormonal axis in the human body. I'll try to offer some science based yet simple answers in a nutshell.

GH has a direct and immediate metabolic effects - it releases glucose and fatty acids to the circulation, meaning it takes stored energy and make it available for the different organs and tissues, this is how it increases metabolism and burns fat both directly (taking fat stored fat and turning it to free fatty acids) and indirectly by expending calories and energy consumption. Note that releasing glucose to the circulation requires the body to secrete insulin immediately in order to balance the glucose levels and lower them back to normal, this mechanism leads with time to decreased insulin sensitivity, as when taking superpharmacological levels of GH the body needs to secrete constantly relatively high amounts of insulin. So GH increases insulin levels and decreases insulin sensitivity (which may bring to insulin resistance in extreme cases - diabetes)

GH has a direct and immediate anabolic effect in the body - it causes different tissues (above all muscle) to retain nitrogen which leads to a positive nitrogen balance = anabolism. It also causes the body to retain minerals (sodium, potassium, calcium, phosphorus) as part of its anabolic effect as well, which explains the quite noticeable and fast water retention many users experience with GH.

Having said and explained that many of the muscle building properties of GH are mediates by IGF1 which is considered the most anabolic hormone in the body. Even if we block somehow the IGF1 secretion which is induced by GH it'll still retain some of its anabolic and metabolic effects directly through GH receptors in different tissues, but big portion of the effect will be abolished, this is why in rare condition when short statue children don't respond well to GH treatment they're teated with IGF1 (prescribed Increlex - you my refer for some info for instance to https://www.eroids.com/forum/hgh-peptides/rhgh/somedin-igf1-lr3-vs-incre...). The GH causes IGF1 secretion from target organs such as the liver and kidneys, and the IGF1 travels in the serum to different tissues (endoctine effect). The GH also causes a local section of IGF1 (and other growth factors) on different tissues, mainly on muscle tissue, it's called autocrine effect, and it's responsible on the stimulation of cell division, and this explains some of the unique so desired effect of GH (and IGF1).

While the direct anabolic effects of GH are quite immediate (though not as prominent as the effects of anabolic steroids), the autocrine effect takes time and requires constant exposure to effective dosages.

GH has another important effect - it directly triggers fibroblast activity, which means recuperation and creation of connective tissue, this of course enables optimal recuperation from injury, this trait enables better strength=muscle gains with time. Like the phenomena of new muscle fiber creation it the fibroblasts activity takes longer time to become pronounced, connective tissue is the slowest to be build and/or recuperate.

The GH is used in the medical field as a short term anabolic aid for post trauma/surgery/severe-burns so yes short term of a couple of month certainly has its benefits, and will create some new muscle fibers to some extent, but as athletes knows GH really shines in long term usage

Sciroxx's picture

I've been asked on GH usage numerous times, I find this post a good starting point so would like to bump it

growthman's picture

Good post +1

Makwa's picture

I have found short term use of GH to be a great benefit. Typically only time I run GH now is when I am on cycle. What I do notice from using it on cycle is that it takes longer for my bodyfat to creep up so I can therefore stay in a longer bulking phase while cyclic bulking and a shorter cut/reset phase. Now with IGF in the mix I can pretty much bulk the entire cycle without a cut/reset phase to bring back my insulin sensitivity. You can see how this is going to aid in lbm over the course of the cycle. Cycling the IGF takes care of the insulin reset phase so I can pretty much stay on a continual bulk while on cycle. Never used the GH for long term use when off cycle though.

simonmagus84's picture

Sorry to bump such an old thread but you make an Excellent point on staying relatively lean during a long bulker,I’ll try this the next time I run Deca. I always looked to take GH off cycle so I have some kind of boost without necessarily taking AAS.

krisandlou0812's picture

Thanks for the post. There is much to learn about using GH. The more educated posts like this help a lot. And it is simple to read. When I start reading something that soudnds like it came from a medical textbook, is when it gets confusing. lol

Trenabolic's picture

IMO if you can’t afford good gh don’t bother. It isn’t the end all be all some would like you to think. On a short budget, can’t beat some good old juice. With that said I loves me some gh, been using it for years.

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333's picture

A 7' 14 year old dam you must of been running gh since birth but i think you should really focus on food intake and diet your a little light for your height

Trenabolic's picture

Well played Smile

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Cummin apart's picture

Nice read! You have a few double post in there though

Gymjunkie01's picture

Wow great post, I think I’m going to run a little to see if it has any effects on my knees

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