posted Fri, 07/26/2019 - 14:16
2272
Aromasin vs Anastrozole for TRT?
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So for the past two years I’ve always been prescribed Anastrozole for my TRT, but it would seem that Aromasin has become the AI of choice for many people on cycle now a days. I got curious and wonder how many of you use Aromasin as your AI on TRT and how it compares to Anastrozole for you.
One of the reasons I’m thinking of asking my Dr about switching is because my lipids are a bit high as of last bloodwork. I just started taking fish oil and niacin to help get them back in range, but have read that Anastrozole can cause them to be high.
Just an update:
Doctor doesn’t want to switch to Aromasin, wants to keep me on Anastrozole for and play with the dosage and timing more.
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I use Anastrozole when on TRT and Aromasin/Exemstane on Cycle, though I have it available if e2 gets out of hand when off. Both can crash e2, though Anastrazole can let you rebound easier, like shiva4 said. I inject 2x/wk, but I've had e2 problems in the past (possibly from low dose Clomid), 0.25-0.25mg of Anastrozole per week at injection times has kept everything in line for me on average-to-high TRT doses.
I have always preferred AROMASIN myself.
Alphamale500Not just arimidex, but even testosterone itself fucks with your lipids. Especially lowering your HDL, or good cholesterol values. But you're absolutely right, aromasin is better for your lipids than arimidex, particularly your HDL levels. I'm currently using arimidex but I have aromasin that I plan on switching to very soon.
My lipid profile is actually very good. The only part that's just a little bit out of range is my HDL levels which are just a tad low. But even my doctor said that they're only so slightly out of range that he wouldn't even treat such values. I also take fish oil/omega 3's, CoQ10, niacin, Provinal omega 7, aged garlic extract with plant sterols etc.. I really believe in maintaining optimal health with the best and most effective vitamins and supplements.
Which of your lipids are out of range? Is it your LDL, HDL, Triglycerides or total cholesterol? I've been using many different vitamins and supps for a long time, and I'm in excellent health to spite the bad shit I put in my body! Maybe I can point you in the right direction of some of the most effective supps that I use?
I just bought red yeast rice, niacin, and omega 3 oil. Hopefully that will help!
As of last bloods:
Triglycerides 126 mg/dL
HDL 54 mg/dL
Cholesterol 216 mg/dL
LDL 137 mg/dL
Non-hdl 162 mg/dL
Have you had any retests after the addition of these supplements?
Alphamale500Alright, so your lipids are pretty good! Triglycerides are perfect, as is your HDL. Your totol cholesterol is a little high. It shouldn't be over 200. And your LDL shouldn't be over 100. Non-HDL should be 130 or less. But they're not way out of wack. The ones you should really try and better is your LDL and of course your total cholesterol too. But they're not that high.+
The niacin and omega 3's are good but the red yeast rice is known to have some sides to worry about. Idk for sure because I stay away. I use a bunch of vitamns and supps. But the ones that are mainly to help my heart and cardiovascular system/lipids are; high dosed extended release B complex with niacin, fish oil 1200mg (EPA/DHA 360mg) softgels, Kyolic Aged Garlic with Plant Sterols, CoQ10, Pumpkin seed oil, Reveratrol and Pterostilbene.
I like to use the extended release niacin so I don't get a niacin flush. If you've never heard of it, it can give you a red, itching, burning rash that's really fckn annoying bro. You should really look into the Resveratrol and Pterostilbene. They have many anti-cancer and anti-aging properties etc.. The garlic has many healthy benefits too.
I'm a big believer in using the best, most effective supps to help prevent/counter any possible sides or even regular ailments that come with aging or unhealthy living habits. Even though I do spend a decent amount on all my vitamins, supps etc, it seems to be working for me and paying off.
My lipids and my latest complete bloodwork are in my pics under my profile if you wanna check them out.
Many physicians opt for anastrozole because it temporarily binds to the enzyme. Aromasin is a suicide inhibitor, meaning once it binds to aromatase it's done for. Anastrozole can lead to fluctuations because of the possibility of rebound but at the same time it can mimic natural physiological processes. This can be very beneficial if your estrogen ends up crashing at some point, there will be a shorter time before your body can return to a homeostatic level of estrogen.
Aromasin tend to be more expensive but anastrozole can effect a small.amount of people in terms of lowering cognitive function. Some physicians dont want to consider this but I can say from personal experience it definitely can for some people.
It all come down to what works best for you. It's really frustrating when a MD wont even consider trying an alternative medicine to see if that works better for the patient.
It comes down to trial and error to find the med and dose that works best for you in terms of balance and side effects.
Just out of curiosity, what is your sugar, fiber and alcohol intake typically?
Alcohol is rarely, and when I do it’s 2 “drinks” (1.5oz liquor) with dinner or friends. You don’t shoot the good stuff.
Fiber could use a little work tbh, usually around 30-40g.
Sugar I try to keep low, aim for under 100g.
Alphamale500If you're thinking of adding some fiber to your diet, then you should try adding some prebiotic soluble fiber, like Inulin. It not only increases your fiber intake, but soluble fiber is very good for lowering your bad (LDL) cholesterol and triglycerides, and raising your good (HDL) cholesterol.
Another great benefit of using Inulin soluble fiber is that it's made from chicory root, and chicory root also has liver protection benefits and other great health benefits as well. So you're killing many birds with one stone, lol!
Have you thought about lowering your TRT dose or if your bf is high lowering that also so don’t have to run an ai?
I have considered it. Bf hovers between 12 and 14% on calipers, and my body burns through test super quick. Day after injection I’m in the high 600s and by the end of the week I’m in the mid 300s. I lowered my injections to 150mg/wk and it did not go well, I became moody and felt like I was fluctuating too much. Dr bumped me back up to 200 and I haven’t had any issues. Also since my SHBG is so low, practically all my estrogen is free. Gotta keep in at the low end or it causes side effects even in the normal range.
Bi weekly injections? You could try a lower dose split e3.5d? I don’t really know much on the subject myself but I know that helps with fluctuations.
I have asked for aromasin for that exact reason. The response I got was that it isn't an AI they consider it a steroid which isn't approved for the treatment. I just shake my head. The problem we face with dr's are they parrot what the fda and big pharma say. A lot of these meds are not "approved " for men to use. I don't like anastrozole for the reason of rebound if you don't take it right or quit taking it. To where aromasin is suicidal. So when the does runs out you don't have to deal with all its captured enzymes being released.
I wonder if they could do an off label prescription for it. I’ll keep y’all updated on what my doctor says
Right on
I prefer Aromasin; just my opinion.
X2
Aro is always my first choice!