Hamm's's picture
Hamm's
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Long term hgh use and insulin resistance.

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I've been using hgh for 5 years at mostly lower doses.
I'm currently at 3ius of a proven generic 5 days a week.
I worry about insulin resistance so I started monitoring my glucose levels.
My levels throughout the day are always normal. Before and after meals - however upon waking my levels are a bit high 110 - 120 range. These levels drop within a couple of hours into the normal range.
Any feedback would be welcomed.

Achak's picture

You should be cycling on/off HGH. I do 6 months on HGH and then switch to 6 months on GHRPS. I take an insulin mimetic supplement with my meals ED. I also take 200mcg of Huperzine A 3x a day to reduce the suppression of natural HGH production.

BJ's picture

Like anything!! if you clean for a while your body will reset itself. Take a break from GH. eat lower carbs for a while & retest your fasted glucose in the morning!

herktime's picture

The body surges insulin to jumpstart you with quick energy 30 minutes prior to waking. Probably why you have higher levels in the morning. Igf-1 combined with gh will level some of the insulin sensitivity issues. I personally think it’s too complicated for a general answer, there are several isomers from two main genes that are so far a mystery to us except that we know 20 kdh is the main pituitary hgh but it’s 22 kdh is released with it and has some different pharmacokinetics that may be mere minutiae Or may selectively perform functions that change the secondary cascade of changes gh sets in motion. The other gene mostly makes a gh particular to the uterus and strongly present during pregnancy. Nobody talks about what gh they got but I saw a lab saying 99% gh but it was the less common pituitary strand and I won’t name them brand but it bummed me out because I don’t know what the downstream differences will be, especially over long term. The thing you must realize is igf binds to a matrix of transporters and carriers that take most of the igf increase and force it to certain tissues where it binds and has a paracrine effect, but often this helps insulin route towards places where it’s not gonna cause sensitivity issues such as the IRBP-1 along the neuronal pathways where Astrocytes can scoop it up and deliver glycogen to the brain. The brain never will prefer any other fuel source, at least exclusively, and uses so much energy and resources that higher insulin during times when you need it and igf to be swept along for repair and growth is not necessarily bad. GLUT-2 and GLUT-4 will transport glucose in critical support for heart and brain and even muscle, too, but most musculature we’re interested in have strong, dense igf-1 receptors so free, unbound igf wil go straight to muscle and hopefully that keeps your body even just micturating excess insulin if it’s not needed despite the increase. Getting your urine and blood sampled for IGF-1 and insulin tell you a lot about where the igf-1 is going, as well as if you are lucky enough to piss insulin before it ha ha around and sensitizes crucial tissue and organs. But keep an eye on it and manage any hypoglycemic And hyperglycemic symptoms. Especially if you’re covalence and gated ion channels are wrenched open by excessive water retention. Hydrocephalus can be mild but extremely dangerous. You really don’t want to see much bloat with rhGH, in my opinion.

Sciroxx's picture

REDACTED

You know better than that... don't be a Karl.

Achak's picture

I take an insulin mimetic and nutrition partitioning agent supplement 2x a day with my highest carb meals. The supplement has multiple ingredients backed by studies that have shown to increase muscle insulin sensitivity and improve blood sugar. Just Google what I wrote above. You'll find multiple brands. Review the ingredients of each one. Go to SelfHacked and research the ingredients. You'll then be able to make an educated decision on which one is best for you.

Nightkrawler451's picture

Hey bro go to YouTube and watch some of Collette Nelson’s videos on Insulin. She is a type 1 diabetic and an expert on insulin. Metformin may work for you but the initial gastric side effects are unpleasant and it also lowers IGF1 levels. A better alternative would be a long acting basal insulin like Lantus or the newer ones like Tresiba etc. Unfortunately you need a prescription for anything but regular insulin.

Gzerored1's picture

I talked to my physician about potentially adding hgh to my hrt regimen due to low igf and he brought up insulin resistance. I believe he said it is best to take the hgh shot some time away from any meals to prevent the insulin resistance.

baol's picture

What was your bg before hgh? Fasting value is taken at what distance from hgh injection? An increase in the fasting glucose value is a consequence of the mobilization induced by the use of hgh; to evaluate whether this value is actually becoming a problem, the H1AC must be evaluated.

Owes a Review × 1
Hamm's's picture

I just ordered some berberine off Amazon and will give it a shot.
Also going to take a break from the growth for a while and see what happens.
Thanks for the info.

DfromPhilly's picture

https://www.eroids.com/forum/general/general-talk/can-berberine-replace-...

Could be helpful. This worked wonders for my buddy who was in the same position as you. He’s in phenomenal shape but is pre-diabetic and was also using low dose growth. I also use it all the time and run growth at 2iu year round and my levels are all solid.

Seems to not work 100% for everyone but there’s a lot of success stories out there. Might be worth giving a try